Evaluation of Balance and Physical Performance Under Dual Task Conditions in Individuals With and Without Generalized Joint Hypermobility

NCT07044999 | Not Yet Recruiting

• 1 other identifier: BeylikduzuStateH22
• Study Type: observational
• Target: 2
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to evaluate balance and physical performance under dual task conditions in individuals with and without Generalized Joint Hypermobility (GJH), as determined by the Beighton score. All participants will undergo the One-Leg Stance Test and 30-Second Sit-to-Stand Test under both single-task (balance only) and dual-task (simultaneous cognitive task) conditions. The cognitive task will involve counting backward by sevens from a given number. Participants will also complete the Timed Up and Go (TUG) test under both single- and dual-task conditions. Additionally, the Berg Balance Scale (BBS) will be used for comprehensive balance assessment. Balance confidence will be evaluated using the Activities-specific Balance Confidence Scale (ABC-16), and fear of falling will be assessed with the Falls Efficacy Scale-International (FES-I). Changes in performance under dual-task conditions will be expressed as a percentage using the Dual Task Cost (DTC) formula

Conditions

Hypermobility Syndrome

Outcome Measures

Primary Outcomes (4)

• Performance in the One-Leg Stance Test

  Assesses static balance capacity and the impact of a simultaneous cognitive task on postural control.

  0 day

• Performance in the 30-Second Sit-to-Stand Test

  Evaluates lower extremity muscle endurance and functional strength under cognitive load

  0 day

• Performance in the Timed Up and Go (TUG) test

  Measures dynamic balance, mobility, and the ability to maintain performance during divided attention.

  0 day

• Dual Task Cost (DTC) percentage

  Quantifies the percentage change in performance when a cognitive task is added, reflecting dual-task interference.

  0 day

Secondary Outcomes (3)

• Berg Balance Scale (BBS):

  0 day

• Activities-specific Balance Confidence Scale (ABC-16)

  0 day

• Falls Efficacy Scale-International (FES-I):

  0 day

Study Arms (2)

patients with hypermobility

Other: no intervention

Control group

Other: no intervention

Interventions

no intervention OTHER

no intervention

Control group; patients with hypermobility

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

hypermobile patients and healthy controls

You may qualify if:

• Aged between 18 and 40 years
• A Beighton score of 4 or higher (indicative of Generalized Joint Hypermobility)
• Willingness to participate in the study

You may not qualify if:

• Younger than 18 or older than 40 years
• Presence of neurological disorders (e.g., stroke, multiple sclerosis, peripheral neuropathy)
• History of vestibular system disorders (e.g., benign paroxysmal positional vertigo, vestibular neuritis)
• History of orthopedic conditions affecting the lower extremities (e.g., fracture, joint replacement, ligament injury)
• Cognitive impairment preventing the execution of cognitive tasks
• Diagnosis of systemic musculoskeletal diseases (e.g., rheumatoid arthritis, Ehlers-Danlos syndrome)
• Pregnancy
• Participation in balance training or neurological/physiotherapy programs within the last 6 months

Sponsors & Collaborators

• Beylikduzu State Hospital: lead

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle Investigator

Study Record Dates

• First Submitted: June 22, 2025
• First Posted: July 1, 2025
• Study Start: July 1, 2025
• Primary Completion: August 1, 2025
• Study Completion: August 1, 2025
• Last Updated: July 1, 2025

Record last verified: 2025-06