A Computer-based Memory Strategy Training Program for Older Adults

NCT07039708 | Recruiting

• 1 other identifier: HongKongPU_E-MinD Life Semanti
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

A computer-based cognitive rehabilitation program based on daily tasks utilising the semantic encoding strategies called Enhancing Memory in Daily Life (E-MinD Life) has been developed for Chinese people. The aim of the E-MinD Life is to delay functional deterioration associated with possible cognitive changes in healthy older adults, older adults with memory complaints, mild cognitive impairment (MCI) and mild dementia. This project will pilot-test the E-MinD Life in Chinese healthy older adults, older adults with memory complaints, MCI and mild dementia.

Conditions

Healthy Older Adults; Memory Complaints; Mild Cognitive Impairment (MCI)

Keywords

computer-based; memory training; activities of daily living; older adults; feasibility

Outcome Measures

Primary Outcomes (1)

• Accceptability

  Acceptability is measured using a structured questionnaire divided into five sections: (1) the therapist-led group sessions, (2) the self-administered individual sessions, and (3) the computer program interface and iPad usability, (4) the overall program design and structure and (5) overall satisfaction. Participants are invited to give quantitative ratings on four dimensions under each section: (a) perceived effectiveness (e.g., whether the program improved cognitive strategy use), (b) relevance (e.g., how applicable the activities were to daily life), (c) convenience (e.g., ease) and (d) clarity. Responses are collected using a 4-point Likert scale, ranging from 1 "Completely disagree" to 4 "Completely agree," with higher scores indicating greater acceptability.

  End of the intervention at 9 weeks

Secondary Outcomes (6)

• Feasibility by measuring the attendance rate

  Through the intervention for 9 weeks, attendance at each session

• Consortium to Establish a Registry for Alzheimer's Disease - Neuropsychological Assessment Battery (CERAD-NAB)

  From enrollment to the end of intervention at 9 weeks

• Digit Span Test

  From enrollment to the end of intervention at 9 weeks

• Lawton Instrumental Activities of Daily Living Scale

  From enrollment to the end of intervention at 9 weeks

• Disability Assessment for Dementia (DAD)

  From enrollment to the end of intervention at 9 weeks

Study Arms (2)

E-MinD Life Semantic

EXPERIMENTAL

Participants receive the E-MinD Life (Semantic) programme.

Behavioral: E-MinD Life Semantic

Cognitive stimulation

ACTIVE COMPARATOR

Participants will receive cognitive stimulation.

Behavioral: Cognitive stimulation

Interventions

E-MinD Life Semantic BEHAVIORAL

The E-MinD Life programme is designed to teach semantic memory strategies. The memory strategies are applied to 12 common daily activities required for community living, e.g. meal preparation, laundry activities, and built into the E-MinD Life programme on a computer-based platform. The intervention runs over 9 weeks with one 45-minute individual face-to-face or online healthcare-professional-led session and two 30-minute, family-assisted home sessions per week. During the home sessions, participants will complete the same activities as those learnt during the healthcare-professional-led sessions. Family members or carers will be invited to join the healthcare-professional-led sessions as observers and support the participants in the home sessions if needed.

E-MinD Life Semantic

Cognitive stimulation BEHAVIORAL

Participants will receive stimulation for visual attention and memory through activities such as playing a game that requires them to find missing pieces, and auditory attention and memory through activities such as remembering a song. The intervention will adopt a similar structure as the E-MinD Life Semantic group, with one 45-minute individual face-to-face or online healthcare-professional-led session and two 30-minute, family-assisted home sessions per week for 9 weeks.

Cognitive stimulation

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Group 1: healthy older adults aged 65 years or above Group 2: older adults aged 65 years or above with memory complaints Group 3: older adults aged 65 or above with mild cognitive impairment

You may not qualify if:

• \- have depression and other clinical conditions that may affect their cognition.

Sponsors & Collaborators

• The Hong Kong Polytechnic University: lead

Study Sites (1)

The Hong Kong Polytechnic University

Hong Kong, Hong Kong, Hong Kong

RECRUITING

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Officials

• Karen Liu

  The Hong Kong Polytechnic University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Karen Liu

CONTACT

+85227665386; karen.liu@polyu.edu.hk

Karen Liu

CONTACT

karen.liu@polyu.edu.hk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: June 18, 2025
• First Posted: June 26, 2025
• Study Start: February 10, 2025
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: September 19, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

HK (1)