Adolescents and Young Adults With Cancer: Their Preferred Involvement in Decision Making

NCT07035418 | Recruiting

• 2 other identifiers: IRB-58292NCI-2024-00875
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this mixed-methods study is to determine Adolescent and Young Adult (AYAs) decision making preferences post cancer diagnosis using vignettes designed to assess their preferred involvement in decisions about their cancer treatment and variables associated with these treatment decision-making (TDM) preferences.

Conditions

Adolescent Behavior

Keywords

Cancer; Survivor; Adolescent and Young Adults

Outcome Measures

Primary Outcomes (1)

• Distribution of Decision-Making Roles in Clinical Scenarios

  Proportion of participants who select an active, collaborative, or passive role in hypothetical clinical decision-making scenarios. Each role will be counted and compared across participant subgroups.

  Within 2 weeks of survey link delivery

Secondary Outcomes (3)

• Association Between Sociodemographic Characteristics and Decision-Making Role

  At time of electronic survey completion

• Concordance Between Interview Responses and Scenario-Based Decision-Making Roles

  At time of interview, within 4 weeks of survey completion

• Correlation Between Healthcare Encounters and Decision-Making Role Preference

  At time of interview, within 4 weeks of survey completion

Study Arms (1)

AYA Decision-Making Role Assessment

EXPERIMENTAL

Participants will complete an electronic socio-demographic questionnaire followed by a set of hypothetical clinical decision-making scenarios to assess preferred decision-making roles and involvement of healthcare providers and family/friends. Responses will inform understanding of facilitators and barriers to shared decision-making.

Behavioral: Clinical Decision-Making Scenarios and Preferences Assessment

Interventions

Clinical Decision-Making Scenarios and Preferences Assessment BEHAVIORAL

Participants complete a socio-demographic questionnaire and decision-making preferences scale, including hypothetical clinical scenarios, to identify their preferred decision-making role (active, collaborative, or passive) and the influence of providers or family. Delivered electronically via secure link; reminders sent as needed.

AYA Decision-Making Role Assessment

Eligibility Criteria

• Age: 15 Years - 29 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Age (15-29 years)
• Cancer diagnosis and on therapy, end-of-life or survivors (within 1 year)
• Speaks English
• Reads English
• Cognitively and physically able to participate

You may not qualify if:

• Unable to participate in study due to developmental delay or developmental disorder

Sponsors & Collaborators

• Stanford University: lead

Study Sites (1)

Stanford University

Palo Alto, California, 94304, United States

RECRUITING

MeSH Terms

Conditions

Adolescent Behavior; Neoplasms

Condition Hierarchy (Ancestors)

Behavior

Study Officials

• Kimberly Pyke-Grimm

  Stanford University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Swathi Alagandula

CONTACT

650-725-1976; drswathi@stanford.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 6, 2025
• First Posted: June 25, 2025
• Study Start: August 23, 2022
• Primary Completion (Estimated): August 1, 2026
• Study Completion (Estimated): August 1, 2026
• Last Updated: February 27, 2026

Record last verified: 2026-02

Locations

US (1)