Lidocaine vs. Lidocaine With Dexmedetomidine for Intravenous Regional Anesthesia (IVRA) in Upper Limb Surgery
Comparison of Lidocaine Alone Versus Lidocaine With Dexmedetomidine for Intravenous Regional Anesthesia (IVRA)
1 other identifier
interventional
90
1 country
1
Brief Summary
This study compares lidocaine alone vs. lidocaine with dexmedetomidine in Intravenous regional anesthesia (IVRA) for upper limb surgery in terms of pain scores and duration of analgesia
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for phase_4 postoperative-pain
Started May 2025
Shorter than P25 for phase_4 postoperative-pain
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 21, 2025
CompletedFirst Submitted
Initial submission to the registry
June 15, 2025
CompletedFirst Posted
Study publicly available on registry
June 24, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 21, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2025
CompletedJune 24, 2025
June 1, 2025
3 months
June 15, 2025
June 15, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Duration of Postoperative Analgesia
Time from surgery to first request for pain relief
Up to 24 hours post surgery
Secondary Outcomes (1)
Pain Score according to Visual Analogue Scale (VAS)
2 hours post-operation
Study Arms (2)
Lidocaine
ACTIVE COMPARATORIntravenous Regional Anesthesia with 40 ml of 0.5% lidocaine
Lidocaine with Dexmedetomidine
EXPERIMENTALIntravenous Regional Anesthesia with 40 ml of 0.5% lidocaine + dexmedetomidine (0.5 μg/kg)
Interventions
Eligibility Criteria
You may qualify if:
- American Society of Anesthesiology Status I
- American Society of Anesthesiology Status II
- Elective surgery
- Surgery duration \<45 minutes
You may not qualify if:
- Sleep apnea
- BMI \>30
- Heart block
- uncontrolled hypertension
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Anesthesiology, Fatima Memorial Hospital
Lahore, Punjab Province, 55000, Pakistan
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Muhammad M Younas, MBBS
Fatima Memorial Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
June 15, 2025
First Posted
June 24, 2025
Study Start
May 21, 2025
Primary Completion
August 21, 2025
Study Completion
August 31, 2025
Last Updated
June 24, 2025
Record last verified: 2025-06
Data Sharing
- IPD Sharing
- Will not share
Individual participant data will not be shared due to institutional policy and data privacy considerations. The data are not intended for secondary use beyond the scope of this study.