Comprehensive Geriatric Assessment in Chronic Disease Management for Older Adults in China: A Registry Study （CGACDM - Older Adults in China）

NCT07033871 | Not Yet Recruiting

• 1 other identifier: HenanPPH-CGA
• Study Type: observational
• Target: 1,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

With the continuous development of China's economy and the improvement of medical standards, the life expectancy of the Chinese population has significantly increased. Against the backdrop of accelerating aging in China, the incidence of age-related chronic non-communicable diseases (NCDs), such as cardiovascular and cerebrovascular diseases and chronic respiratory diseases, has risen remarkably. These diseases are characterized by multiple comorbidities, high disability rates, and high mortality rates, severely compromising the quality of life of older adults, exacerbating family burdens, and straining healthcare systems. This constitutes one of the major challenges faced by aging societies. Therefore, early detection and intervention of chronic diseases in older adults are critical measures to address population aging. Comprehensive geriatric assessment (CGA), a core specialty of geriatric medicine, serves as a fundamental framework for the clinical identification of geriatric syndromes and multidisciplinary management. It is emerging as a key pathway to promote "healthy aging." Guided by this premise, this study aims to explore the application value of CGA in managing chronic diseases among older adults, with the goal of achieving full-cycle management for early detection, diagnosis, and treatment of chronic conditions in China's elderly population.

Conditions

Comprehensive Geriatric Assessment; Chronic Disease Management; Older Adults (65 Years and Older)

Keywords

Comprehensive Geriatric Assessment; Chronic Disease Management; Older Adults

Outcome Measures

Primary Outcomes (1)

• Major adverse events (MAE)

  Major adverse events (MAE) in overall population, defined as composite of all-cause death, Heart Failure hospitalization, recurrent myocardial infarction, stroke, etc.

  These data is collected during follow-up visit at 3/6/12/24/36 months after discharge

Other Outcomes (33)

• Age for each participant

  These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

• Gender for each participant

  These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

• Height for each participant

  These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

Study Arms (2)

Elderly patients with chronic diseases

The study population consisted of patients with chronic diseases in the elderly who underwent comprehensive geriatric assessment and management. Chronic diseases in the elderly included but were not limited to chronic heart failure, chronic obstructive pulmonary disease, cognitive dysfunction, and so on. We compared various biochemical indexes, cardiac function indexes, quality of life, and the occurrence of long-term adverse events before and after the comprehensive geriatric assessment and management.

Diagnostic Test: comprehensive geriatric assessment

Healthy elderly population

The control group was composed of elderly subjects without evidence of chronic diseases. Chronic diseases was excluded by performing a complete medical history, a comprehensive physical examination, and an echocardiogram.

Diagnostic Test: comprehensive geriatric assessment

Interventions

comprehensive geriatric assessment DIAGNOSTIC_TEST

The comprehensive geriatric assessment (CGA) is a multi dimensional diagnostic process used to determine the medi cal, psychological, and functional capabilities of a frail elderly person to develop a coordinated and integrated plan for treat ment and long-term follow-up.

Elderly patients with chronic diseases; Healthy elderly population

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of patients with chronic diseases in the elderly who underwent comprehensive geriatric assessment and management. Chronic diseases in the elderly included but were not limited to chronic heart failure, chronic obstructive pulmonary disease, cognitive dysfunction, and so on.

You may qualify if:

• \. Aged 60 years or older 2. Diagnosed with chronic diseases in the circulatory, respiratory, digestive, nervous, or endocrine systems, consistent with corresponding disease diagnostic criteria; 3. Availability of complete medical records; 4. Clear consciousness and ability to independently answer questions; 5. Signed informed consent form.

You may not qualify if:

• \. Presence of any condition/circumstance which in the opinion of the investigator could significantly limit the complete follow up of the patient (e.g. tourist, non-native speaker or does not understand the local language, psychiatric disturbances).
• \. Presence of serious/severe co-morbidities in the opinion of the investigator which may limit short term (i.e. 6 month) life expectancy.
• \. Current participation in a randomised interventional clinical trial.

Sponsors & Collaborators

• Henan Provincial People's Hospital: lead
• Geriatrics Research Institute of Henan Provincial People's Hospital: collaborator
• Beijing Institute of Heart, Lung and Blood Vessel Diseases: collaborator

Central Study Contacts

Yang Xinying Yang Xinying

CONTACT

0371-87160164; xinyingyang150@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 26, 2025
• First Posted: June 24, 2025
• Study Start: July 1, 2025
• Primary Completion (Estimated): May 1, 2030
• Study Completion (Estimated): May 1, 2030
• Last Updated: June 24, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share