Uroflowmetry and Nocturnal Enuresis

NCT07028645 | Active Not Recruiting FDA Drug

• 1 other identifier: Ivstrh - UF PMNE
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This study will evaluate the uroflowmetry parameters of patients which were treated for enuresis.

Conditions

Enuresis, Nocturnal

Keywords

Uroflowmetry; Enuresis

Outcome Measures

Primary Outcomes (1)

• Number of days without bedwetting

  Achievement of bedwetting in one or less night of a month

  1 month

Study Arms (3)

Desmopressin 120mcg

Patients treated with desmopressin 120 mcg

Drug: desmopressin melt form 120 μg

Desmopressin 240 mcg

Patients treated with desmopressin 240mcg

Drug: Desmopressin lyophilisate (Melt)

Desmopressin 240 mcg + anticholinergic

Patients treated with desmopressin 240mcg + anticholinergic agent

Drug: Propiverine tablet

Interventions

desmopressin melt form 120 μg DRUG

Desmopressin 120 mcg will be used frist-line drug in the treatment of enuresis.

Desmopressin 120mcg

Desmopressin lyophilisate (Melt) DRUG

Desmopressin 240 mcg will be used for the patients who have not responsive to desmopressin 120 mcg.

Desmopressin 240 mcg

Propiverine tablet DRUG

Propiverine (a dose of 0.8 mg/ kg) will be used for the patients who have -response to treatment with desmopressin 240 mcg

Desmopressin 240 mcg + anticholinergic

Eligibility Criteria

• Age: 5 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Patients who were treated for enuresis in pediatric urology clinic of Sancaktepe Sehit Prof Dr Ilhan Varank Training and Research Hospital

You may qualify if:

• Presence of enuresis nocturna
• Patients who have uroflowmetry test

You may not qualify if:

• Presence of lower urinary tract symptoms
• Presence of anatomical or neurological problems
• Patients with missing data

Sponsors & Collaborators

• Furkan Adem Canbaz: lead

Study Sites (1)

Sancaktepe Sehit Prof dr Ilhan Varank Training and Research Hospital

Istanbul, Kadikoy, 34000, Turkey (Türkiye)

Location

Related Publications (1)

• Kang BJ, Chung JM, Lee SD. Evaluation of Functional Bladder Capacity in Children with Nocturnal Enuresis According to Type and Treatment Outcome. Res Rep Urol. 2020 Sep 15;12:383-389. doi: 10.2147/RRU.S267417. eCollection 2020.

  PMID: 32984086 BACKGROUND

MeSH Terms

Conditions

Nocturnal Enuresis; Enuresis

Interventions

Freezing; propiverine

Condition Hierarchy (Ancestors)

Urination Disorders; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Behavioral Symptoms; Behavior; Elimination Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Phase Transition; Physical Phenomena; Cold Temperature; Temperature; Thermodynamics; Chemical Phenomena

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Medical doctor

Study Record Dates

• First Submitted: June 11, 2025
• First Posted: June 19, 2025
• Study Start: August 20, 2022
• Primary Completion: September 1, 2024
• Study Completion: December 30, 2025
• Last Updated: June 24, 2025

Record last verified: 2025-06

Locations

TU (1)