Incidence of Hypotension in the Post-anesthesia Care Unit (PACU).

NCT07022210 | Recruiting

• 1 other identifier: 2025-12
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The perioperative period poses a heightened risk of complications for patients, including hypotension. While the issue of intraoperative hypotension is well-documented in medical literature, the occurrence and causes of hypotension in the post-anesthesia care unit often receive less attention. This phase of postoperative care, however, is vital for ensuring patient stability and preventing severe consequences. Failure to identify and manage a drop in blood pressure can lead to hypoperfusion of critical organs, increasing the risk of morbidity and mortality. The aim of this study is to examine the frequency of hypotension in the post-anesthesia care unit-defined as systolic blood pressure \<90 mmHg or a drop of more than 20% from baseline-and to identify factors contributing to its development.

Conditions

Hypotension During Surgery; Surgery-Complications

Keywords

hypotension; post-anesthesia care unit; surgery; adult

Outcome Measures

Primary Outcomes (1)

• Incidence of hypotension in the post-anesthesia care unit (PACU).

  Hypotension is defined as systolic blood pressure \<90 mmHg or a decrease of more than 20% from baseline values.

  0. postoperative day

Secondary Outcomes (18)

• Duration of the operation

  0. postoperative day

• ASA classification (American Society of Anesthesiologists classification).

  0. postoperative day

• Type of anesthesia.

  0. postoperative day

• Blood loss during the operation

  0. postoperative day

• Fluid balance during the surgery

  0. postoperative day

Eligibility Criteria

• Age: 18 Years - 105 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients meeting the inclusion criteria, aged 18 to 105 years, with an indicated hospitalization at a diagnostic-therapeutic unit (DTU).

You may qualify if:

• patients over 18 years old
• patients undergoing a procedure under general anesthesia
• patients who have consented to data processing
• postoperative stay in PACU

You may not qualify if:

• patients younger than 18 years old.
• patients transferred directly to the ICU/Anesthesiology and Resuscitation Department after surgery without staying in the recovery room.
• patients with incomplete medical documentation or missing blood pressure values in the recovery room.
• patients with a pre-existing diagnosis of resistant hypotension or unstable hemodynamics before surgery
• patients with a history of long-term use of anxiolytics, antipsychotics, or other psychotropic medications that may affect cognitive function, emotional state, or predictive outcomes
• patient refusal to participate in the study (including cases where they initially consented), with an emphasis on respecting patient autonomy

Sponsors & Collaborators

• Tomas Bata Hospital, Czech Republic: lead

Study Sites (1)

Tomas Bata regional Hospital

Zlín, 76001, Czechia

RECRUITING

MeSH Terms

Conditions

Hypotension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Central Study Contacts

Klára Nekvindová, M.D., P.h.D.

CONTACT

+420 577 551 111; nekvindova.klara@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Deputy Chief for Science, Education, and Research

Study Record Dates

• First Submitted: May 22, 2025
• First Posted: June 15, 2025
• Study Start: June 15, 2025
• Primary Completion: May 1, 2026
• Study Completion: May 1, 2026
• Last Updated: July 10, 2025

Record last verified: 2025-06

Locations

CZ (1)