Impact of Door-to-Needle Time on Stroke Outcomes at Gonesse Hospital

NCT07018167 | Active Not Recruiting

• 1 other identifier: 0107_NEUROLOGIE
• Study Type: observational
• Target: 61
• Locations: 1 country
• Sites: 1

Brief Summary

This study looks at how quickly stroke patients receive treatment after arriving at Gonesse Hospital and whether this affects their recovery. Researchers will measure the time between a patient's arrival and the start of clot-busting treatment (called Door-to-Needle Time), as well as the time from symptom onset to hospital arrival (Home-Time). The goal is to see if treatment delays impact recovery, and to find ways to improve stroke care in the hospital.

Conditions

Stroke; Ischemic Attack, Transient; Cerebral Infarction; Thrombolytic Therapy; Treatment Outcome

Outcome Measures

Primary Outcomes (1)

• Time (in minutes) from hospital arrival to thrombolysis (Door-to-Needle Time).

  3 months

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of adult patients (aged 18 and over) admitted to the Gonesse Hospital for acute ischemic stroke. All participants must have received intravenous thrombolysis (r-tPA) initiated at the hospital during the 3-month study period. Only patients with complete clinical and time-tracking data enabling the calculation of Door-to-Needle Time will be included.

You may qualify if:

• Patients aged 18 years or older
• Confirmed diagnosis of acute ischemic stroke on imaging
• Initial acute stroke care provided at Gonesse Hospital during the study period (3 months)
• Intravenous thrombolysis (r-tPA) initiated at the hospital
• Availability of clinical and timing data to calculate Door-to-Needle Time (DNT)

You may not qualify if:

• Patients with hemorrhagic stroke or subarachnoid hemorrhage (SAH)
• Thrombolysis initiated before hospital arrival
• Missing, incomplete, or unusable timing data for DNT calculation

Sponsors & Collaborators

• Centre Hospitalier de Gonesse: lead

Study Sites (1)

France

Gonesse, France, France

Location

MeSH Terms

Conditions

Stroke; Ischemic Attack, Transient; Cerebral Infarction

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Brain Ischemia; Brain Infarction; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 21, 2025
• First Posted: June 12, 2025
• Study Start: May 1, 2025
• Primary Completion: September 1, 2025
• Study Completion: September 1, 2025
• Last Updated: June 12, 2025

Record last verified: 2025-05

Locations

FR (1)