Double-Lumen Tube Intubation in the Lateral Position Versus the Supine Position on First-Attempt Success Rate

NCT07014345 | Withdrawn

• 1 other identifier: Intubation
• Study Type: interventional
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this clinical trial is to find out the first success rate of double lumen intubation in the lateral position in thoracic surgery, it will also find out the safety of double lumen tube intubation in the lateral position. The trial aims to answer the following key questions Does intubation in lateral position improve the first-time success rate of double-lumen intubation compared with in the supine position? What medical problems can participants experience during double lumen tube intubation in the lateral position? The researchers will compare double lumen intubation in the lateral position vs supine position to see if the position is effective in the success rate of double lumen intubation. Participants will Use the supine or lateral position during intubation

Conditions

Double Lumen Tube Intubation

Keywords

Double-lumen tube; lateral position intubation; first-attempt success rate; thoracic surgery

Outcome Measures

Primary Outcomes (1)

• Successful First-Pass Intubation

  The primary outcome was the success rate of the first DLT intubation attempt.

  Periprocedural

Secondary Outcomes (9)

• No. of intubation attempts

  Periprocedural

• Intubation time

  Periprocedural

• Interval before surgery

  Periprocedural

• p-Peak

  Periprocedural

• Flexible bronchoscope usage

  Periprocedural

Study Arms (2)

DLT placement performed in lateral position

EXPERIMENTAL

In the lateral position group, patients were positioned laterally (as required for surgery) before anesthesia induction. After anesthesia induction, Double lumen tube placement was performed while the patient remained in the lateral position.

Procedure: DLT placement performed in lateral position

DLT placement performed in supine position

NO INTERVENTION

A double-lumen tube is typically carried out with the patient in the supine position, which is a standard procedure in thoracic surgery.

Interventions

DLT placement performed in lateral position PROCEDURE

In the lateral position group, patients were positioned laterally (as required for surgery) before anesthesia induction. After anesthesia induction, Double lumen tube placement was performed while the patient remained in the lateral position.

DLT placement performed in lateral position

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• need for DLT intubation with elective unilateral thoracoscopic surgery
• age 18-65 years
• American Society of Anesthesiologists (ASA) grade of I or II
• no serious cardiopulmonary disease

You may not qualify if:

• aged \<18 years or \>65 years
• body mass index \>30 kg/m2
• cognitive dysfunction and inability to assume the required body position
• previous cervical vertebrae and expected difficult airway (e.g., Mallampati airway grade of III, IV, or higher, maximum mouth opening \<3 finger widths, nail-chin distance \<6 cm)
• admission to the intensive care unit after surgery and without follow-up

Sponsors & Collaborators

• xiangming fang: lead
• Red Cross Hospital, Hangzhou, China: collaborator
• The First Affiliated Hospital of Guangzhou Medical University: collaborator
• Central People's Hospital of Zhanjiang: collaborator
• The Central Hospital of Lishui City: collaborator

Study Sites (1)

China

Hangzhou, Zhejiang, 310000, China

Location

Related Publications (5)

• Kim H, Seol T, Han SH, Kim H, Hwang JY. A bench study on the prevention of lung-to-lung aspiration with double-lumen endobronchial tubes and bronchial blockers. Sci Rep. 2024 Jan 2;14(1):187. doi: 10.1038/s41598-023-50792-z.

  PMID: 38167877 BACKGROUND

• Campos JH. Lung isolation techniques for patients with difficult airway. Curr Opin Anaesthesiol. 2010 Feb;23(1):12-7. doi: 10.1097/ACO.0b013e328331e8a7.

  PMID: 19752725 BACKGROUND

• Brodsky JB. Lung separation and the difficult airway. Br J Anaesth. 2009 Dec;103 Suppl 1:i66-75. doi: 10.1093/bja/aep262.

  PMID: 20007992 BACKGROUND

• Yang M, Kim JA, Ahn HJ, Choi JW, Kim DK, Cho EA. Double-lumen tube tracheal intubation using a rigid video-stylet: a randomized controlled comparison with the Macintosh laryngoscope. Br J Anaesth. 2013 Dec;111(6):990-5. doi: 10.1093/bja/aet281. Epub 2013 Aug 23.

  PMID: 23975566 BACKGROUND

• Saji H, Okada M, Tsuboi M, Nakajima R, Suzuki K, Aokage K, Aoki T, Okami J, Yoshino I, Ito H, Okumura N, Yamaguchi M, Ikeda N, Wakabayashi M, Nakamura K, Fukuda H, Nakamura S, Mitsudomi T, Watanabe SI, Asamura H; West Japan Oncology Group and Japan Clinical Oncology Group. Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial. Lancet. 2022 Apr 23;399(10335):1607-1617. doi: 10.1016/S0140-6736(21)02333-3.

  PMID: 35461558 BACKGROUND

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Chair Professor, Department of Anesthesiology Vice Dean, School of Medicine and and Pharmaceutical sciences Zhejiang University

Study Record Dates

• First Submitted: May 22, 2025
• First Posted: June 11, 2025
• Study Start: December 1, 2022
• Primary Completion: November 30, 2023
• Study Completion: November 30, 2023
• Last Updated: August 14, 2025

Record last verified: 2025-06

Locations

CN (1)