Systems Biology of Amyotrophic Lateral Sclerosis (ALS)
1 other identifier
observational
20
0 countries
N/A
Brief Summary
The goal of this observational study is to identify molecular features in multiple clinical samples and/or the patient environment that are associated with ALS. Participants will collect biological samples and answer questionnaires regarding their health at each appointment with their ALS practitioner.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Jun 2025
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 28, 2025
CompletedStudy Start
First participant enrolled
June 1, 2025
CompletedFirst Posted
Study publicly available on registry
June 5, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2030
ExpectedStudy Completion
Last participant's last visit for all outcomes
May 1, 2030
June 5, 2025
June 1, 2025
4.7 years
March 28, 2025
June 2, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Molecular features of biological samples that are predictive of ALS progression
We will collect samples and health data from each participant from the time of diagnosis to their death or study termination, whichever comes sooner. Specific time frame: We will collect outcome measures through study completion, an average of 3 years.
Study Arms (2)
ALS Cohort
Patients of Dr. Espíndola at UFSC that are diagnosed with ALS and meet the inclusion/exclusion criteria.
Control Cohort
Those that meet the inclusion/exclusion criteria, do not have ALS, and generally are healthy.
Eligibility Criteria
ALS cohort: Patients of Dr. Espíndola at UFSC Control cohort: Participants from the general population
You may qualify if:
- Patient of Dr. Espíndola at UFSC
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Viomelead
- Universidade Federal de Santa Catarinacollaborator
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 28, 2025
First Posted
June 5, 2025
Study Start
June 1, 2025
Primary Completion (Estimated)
February 1, 2030
Study Completion (Estimated)
May 1, 2030
Last Updated
June 5, 2025
Record last verified: 2025-06