Key Insights

Highlights

Success Rate

89% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

2.0%

1 terminated out of 51 trials

Success Rate

88.9%

+2.4% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

38%

3 of 8 completed with results

Key Signals

3 with results89% success

Data Visualizations

Phase Distribution

34Total
Not Applicable (17)
Early P 1 (1)
P 1 (7)
P 2 (9)

Trial Status

Recruiting17
Not Yet Recruiting12
Unknown9
Completed8
Active Not Recruiting2
Suspended1

Trial Success Rate

88.9%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (51)

Showing 20 of 20 trials
NCT07407725Not ApplicableRecruiting

Clinical Outcome Assessment for AT & BCI

NCT06051123Not ApplicableRecruiting

Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients

NCT07543367Not ApplicableNot Yet Recruiting

INdependence Through Endovascular Neuroprosthetic Technology (INTENT): an Early Feasibility Study

NCT07539662Not ApplicableEnrolling By InvitationPrimary

Unrelated Umbilical Cord Blood Transplantation for the Treatment of Amyotrophic Lateral Sclerosis (ALS)

NCT07467187Recruiting

Invasive Home Ventilation in Denmark

NCT06856850RecruitingPrimary

Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical Approaches

NCT07088159UnknownPrimary

Intermediate-size Patient Population Expanded Access Protocol

NCT07491562Not ApplicableRecruitingPrimary

Evaluation of a Structurally Suitable Neck Exoskeleton in Patients With Amyotrophic Lateral Sclerosis

NCT07479017Not Yet RecruitingPrimary

Characterization of Platelet Molecular Profiles in ALS for the Identification of Specific Diagnostic Biomarkers - A Pilot Study

NCT07473765Not ApplicableNot Yet RecruitingPrimary

Virtual Reality for Anxiety Management in Persons With Amyotrophic Lateral Sclerosis

NCT07100119Phase 1RecruitingPrimary

A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis

NCT02164253Phase 2CompletedPrimary

Focal Accumulation of Iron in Cerebral Regions in Early ALS (Amyotrophic Lateral Sclerosis) Patients

NCT07401121Phase 1RecruitingPrimary

Safety and Tolerability Study of CTx1000 In Participants With Amyotrophic Lateral Sclerosis

NCT07400393Not Yet Recruiting

Healey ALS MyMatch Common Screening Protocol

NCT07396818Phase 1Not Yet RecruitingPrimary

Kamlanoflast In Amyotrophic Lateral Sclerosis

NCT07294144Phase 2RecruitingPrimary

Tofersen in Non-SOD1 ALS

NCT06649955Not ApplicableRecruitingPrimary

Controlling Amyotrophic Lateral Sclerosis Motor Neuron Excitability Study

NCT06199284Not ApplicableSuspendedPrimary

Atalante Exoskeleton in the Rehabilitation of Patients With Amyotrophic Lateral Sclerosis

NCT07321860Phase 2Not Yet RecruitingPrimary

This Study Evaluates the Safety, Target Engagement, and Preliminary Efficacy of Galunisertib (TGF-βR1/ALK5 Inhibitor)Combined With Nerandomilast (PDE4 Inhibitor) in GREM2-positive ALS, a Biomarker-defined Subgroup Hypothesized to Reflect Heightened TGF-β/SMAD-driven Astrocytic and Fibrotic Signaling

NCT07295990Not ApplicableNot Yet Recruiting

Tongue-strengthening Exercises in People With ALS.

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