Hair Isotope Analysis for Early Cancer Detection
HI-CARE
1 other identifier
observational
20
1 country
1
Brief Summary
Cancer is a major health challenge, and early detection is crucial for improving patient outcomes. Research has shown that cancer can alter the way the body processes nutrients. This study aims to explore whether these metabolic changes can be detected through a simple, non-invasive method: analysing hair. Hair grows slowly over time, potentially capturing subtle metabolic changes that occur during cancer development. By studying the nitrogen stable isotope composition in hair samples donated by individuals diagnosed with cancer, we aim to identify potential early markers of the disease. Participants will be asked to donate a small strand of hair, which will be analysed using a laboratory technique called Isotope Ratio Mass Spectrometry (IRMS). The findings from this study could contribute to new, non-invasive screening tools for early cancer detection.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Sep 2025
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 27, 2025
CompletedFirst Posted
Study publicly available on registry
June 5, 2025
CompletedStudy Start
First participant enrolled
September 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 30, 2030
ExpectedStudy Completion
Last participant's last visit for all outcomes
May 30, 2030
June 5, 2025
May 1, 2025
4.7 years
May 27, 2025
May 27, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
longitudinal changes in d15N in hair
Longitudinal changes in d15N in hair samples to obtain a time-series
Approximately one year
Eligibility Criteria
Cancer patients in the UK
You may qualify if:
- Cancer diagnosis, sufficient hair
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Reading
Reading, RG6 6DZ, United Kingdom
MeSH Terms
Conditions
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor of Nutrition and Food Science
Study Record Dates
First Submitted
May 27, 2025
First Posted
June 5, 2025
Study Start
September 1, 2025
Primary Completion (Estimated)
May 30, 2030
Study Completion (Estimated)
May 30, 2030
Last Updated
June 5, 2025
Record last verified: 2025-05
Data Sharing
- IPD Sharing
- Will not share
Participation will be anonymous