Comparison Effects of Three Regional Anesthetic Technique on Pain During Video-assisted Thorascopic Surgery(VATS)

NCT06689449 | Active Not Recruiting DMC

• 1 other identifier: 2024/165
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, our iş to compare effect of erector spinae plan block(ESP), paravertebral block(PVB) and mid-point transverse process to pleura block(MTP) on perioperative pain measured with analgesia nociceptive index monitor on video-assisted thoracoscopic surgery.

Conditions

Video Assisted Thoracic Surgery (VATS)

Keywords

video assisted thoracic surgery; erector spinae plan block; paravertebral block; mid-point transverse process to pleura block; analgesia nosiseption index

Outcome Measures

Primary Outcomes (1)

• Effective analgesia control in patients with Analgesia Nociception Index(ANI)

  With Analgesia Nociception Index (ANI), it is advantageous to evaluate the objective findings measuring parasympathetic system activity. ANI is a monitor that can be measured continuously and non-invasively. It measures parasympathetic tone - based on electrocardiography - by analyzing minimal changes in heart rate that occur under anesthesia, in the early stages of awakening, and in each respiratory cycle of awake patients. A value between 0-100 is obtained, Values between 50 and 70 indicate good analgesia control. According to studies on ANI, the patient feels pain below 50. If it is above 70, it means that more analgesia is provided. It is thought that pain control will be more effective with these objective data.

  intraoperative

Secondary Outcomes (1)

• Visual analog scale

  ıntraoperative and postoperative 24 hour

Study Arms (3)

erector spinae plan block group

The patient will be monitored with routine monitoring and ANI under operating room conditions. VAS values and vital signs before and after peripheral nerve block will be recorded. Patients will be placed in the lateral position and an erector spinae plane block will be applied under USG guidance by an experienced anesthesiologist. Surgery will be allowed 30 minutes after the block is performed.

paravertebral block group

The patient will be monitored with routine monitoring and ANI under operating room conditions. VAS values and vital signs before and after peripheral nerve block will be recorded. Patients will be placed in the lateral position and a paravertebral block will be applied under USG guidance by an experienced anesthesiologist. Surgery will be allowed 30 minutes after the block is performed.

mid-point transverse process to pleura block group

The patient will be monitored with routine monitoring and ANI under operating room conditions. VAS values and vital signsbefore and after peripheral nerve block will be recorded. Patients will be placed in the lateral position and a mid-point transverse process to pleura block will be applied under USG guidance by an experienced anesthesiologist. Surgery will be allowed 30 minutes after the block is performed.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

ASA group 2-3-4 patients older than 18 years of age who will under go video assisted thoracic surgery

You may qualify if:

• Patient over the age of 18 under the 80 Who will undergo video assisted thoracic surgery -ASA group 2-3-4.
• Patients without opioid addiction.
• Patients without allergies.
• Patients without psychiatric disorder.
• Patients without arrhymia and beta-blocker use.
• Patients without contraindications for peripheral blocks.

You may not qualify if:

• Patients under age of 18
• Patients undergo surgery under general anesthesia
• Patients undergo emergency surgery
• Patients allergic to local anesthesia
• Patients wit bleeding diathesis

Sponsors & Collaborators

• TC Erciyes University: lead

Study Sites (1)

Recep aksu

Kayseri, Kayseri̇, 38039, Turkey (Türkiye)

Location

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: clinical Professor.Recep AKSU

Study Record Dates

• First Submitted: November 13, 2024
• First Posted: November 14, 2024
• Study Start: November 20, 2024
• Primary Completion (Estimated): October 20, 2026
• Study Completion (Estimated): October 20, 2026
• Last Updated: December 16, 2024

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)