Comparing Erector Spinae and Fascia Iliaca Blocks for Pain Relief After Femur Surgery.

NCT06990958 | Completed DMC

• 1 other identifier: MS-212-2023
• Study Type: interventional
• Target: 92
• Locations: 1 country
• Sites: 1

Brief Summary

This clinical study compares two types of nerve blocks used to control pain in adult patients undergoing surgery on the upper (proximal) or middle (midshaft) part of the femur (thigh bone). The two blocks being studied are the Erector Spinae Plane (ESP) block and the Fascia Iliaca Compartment (FIC) block. Both techniques are commonly used in hospitals to reduce postoperative pain. The goal is to determine which nerve block provides more effective pain relief, reduces the need for opioid medications, and supports faster recovery in patients following femur surgery. Results from this study may improve pain management strategies for similar procedures in the future. Adults scheduled for proximal or midshaft femur surgery may be eligible to participate. Eligibility is determined based on clinical criteria reviewed by the study team.Administration of one of the two nerve blocks before surgery.Standard surgical and postoperative care. Monitoring of pain levels at specific time points after surgery Recording of opioid medication usage Evaluation of patient satisfaction and any side effects related to the nerve block Duration: The intervention (nerve block) is administered once before surgery. Data collection continues during the immediate postoperative period and for a short time following surgery to assess outcomes. Both nerve blocks are considered safe and are regularly used in clinical practice. All procedures are performed by qualified clinicians, and safety monitoring is conducted throughout the study. Participants may experience improved pain relief and reduced need for opioid medications. While direct benefit cannot be guaranteed, information gained from the study may help improve pain management for future patients undergoing similar surgeries. Participation in the study is completely voluntary. Patients may choose not to participate or may withdraw from the study at any time without affecting the quality of their medical care.

Conditions

Analgesia After Fracture Femur Surgeries

Keywords

Fascia iliac block, erector spinae block, femur fracture, adult analgesia

Outcome Measures

Primary Outcomes (1)

• duration of the block

  time starting immediatelyafter giving the block till the first postoperative analgesic rescue which will be used if the pain score exceeds 4/10

  15 minutes after extubation till 24 hours postoperative

Study Arms (2)

ESPB Group

ACTIVE COMPARATOR

patients was placed in the lateral position . the block was performed bz ipsilateral injection of a mixture containing 15mls bupivcaine 0,5% and 20mls normal saline.

Procedure: Erector Spinae Plane Block (ESPB) group

FICB

ACTIVE COMPARATOR

Patients was placed insupine position . the block performed using a mixture of 15mls bupivcaine 0,5% and 20mls normal saline.

Procedure: Fascia iliaca compartment block (FICB)

Interventions

Erector Spinae Plane Block (ESPB) group PROCEDURE

ultrasound guided erector spinae plane block (at lumbar level) in lateral position .

ESPB Group

Fascia iliaca compartment block (FICB) PROCEDURE

ultrasound guided suprainguinal approach in supine position

FICB

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• age 18-80
• American society of Anathesiologist physical status ASA Ior II
• Patients undergoing Fixation of femur fractures

You may not qualify if:

• Refusal of participation in study.
• Bleeding disorders (platelets count \< 80,000, INR \>1.5, Prothrombin concentration \< 60%).
• Skin lesion, wounds or infection at the puncture site. Known allergy to local anesthetic drugs.
• Known local anesthetic (LA) drug sensitivity. -

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

kasr alainy hospital -Cairo university , cairo

Cairo, Egypt

Location

MeSH Terms

Conditions

Femoral Fractures; Agnosia

Interventions

Population Groups

Condition Hierarchy (Ancestors)

Fractures, Bone; Wounds and Injuries; Leg Injuries; Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Demography; Population Characteristics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesia, surgical ICU and Pain Management Faculty of Medicine, Cairo University

Study Record Dates

• First Submitted: May 18, 2025
• First Posted: May 25, 2025
• Study Start: March 5, 2025
• Primary Completion: July 10, 2025
• Study Completion: August 10, 2025
• Last Updated: December 2, 2025

Record last verified: 2025-11

Locations

EG (1)