Comparison Between Ultrasound-Guided Costoclavicular and Lateral-Sagittal Infraclavicular Brachial Plexus Blocks in Adult Distal Upper Limb Surgeries : A Randomized Controlled Trial

NCT07517809 | Recruiting

• 1 other identifier: FMASU MS 101/2026
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to compare the onset time of the costoclavicular approach of brachial plexus block with that of the lateral-sagittal infraclavicular approach in adults distal upper limb surgeries.

Conditions

Regional Anesthesia Block; Brachial Plexus Blocks

Outcome Measures

Primary Outcomes (1)

• Time to onset of complete sensory and motor block

  Time from completion of local anesthetic injection to achievement of complete sensory and motor blockade. Sensory block will be assessed using pinprick testing in the distributions of the median, ulnar, radial, and musculocutaneous nerves. Motor block will be graded using a standardized motor scale. And time will be in minutes and seconds.

  From completion of injection up to 30 minutes after block performance

Study Arms (2)

Lateral-sagittal infraclavicular block (LS-ICB) group

ACTIVE COMPARATOR

Drug : A mixture of 2% lidocaine and 0.5% bupivacaine with volume of 0.3 mL/kg and a ratio of 1:1.

Procedure: Lateral-sagittal infraclavicular brachial plexus block

Costoclavicular block brachial plexus (CC) group

ACTIVE COMPARATOR

Procedure: Costoclavicular brachial plexus block

Interventions

Costoclavicular brachial plexus block PROCEDURE

Ultrasound-guided costoclavicular brachial plexus block performed using a high-frequency linear probe. A mixture of 2% lidocaine and 0.5% bupivacaine (1:1 ratio) with a total volume of 0.3 mL/kg is injected in the costoclavicular space around the cords of the brachial plexus under real-time ultrasound guidance.

Costoclavicular block brachial plexus (CC) group

Lateral-sagittal infraclavicular brachial plexus block PROCEDURE

Ultrasound-guided lateral-sagittal infraclavicular brachial plexus block performed using a high-frequency linear probe. A mixture of 2% lidocaine and 0.5% bupivacaine (1:1 ratio) with a total volume of 0.3 mL/kg is injected around the cords of the brachial plexus under real-time ultrasound guidance.

Lateral-sagittal infraclavicular block (LS-ICB) group

Eligibility Criteria

• Age: 21 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ASA physical status I-III
• Distal upper limb surgery requiring brachial plexus block.
• Patient approval after written and informed consent to participate.

You may not qualify if:

• Patient refusal.
• Allergy to drugs used.
• Infection at puncture site.
• Coagulopathy or anticoagulant therapy.
• Pre-existing neuropathy or neurological deficit in the affected limb.
• Severe pulmonary disease.
• BMI \> 40 kg/m².

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University Hospitals

Cairo, Egypt

RECRUITING

Central Study Contacts

Ahmed Hesham Shahin, M.B.B.CH

CONTACT

+201270857308; 160634@med.asu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 2, 2026
• First Posted: April 8, 2026
• Study Start: February 16, 2026
• Primary Completion (Estimated): August 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: April 8, 2026

Record last verified: 2026-04

Locations

EG (1)