Ultrasound Measurement of Optic Nerve Sheath Diameter as Non-Invasive Detector of Raised Intracranial Pressure in Adult Traumatic and Non-Traumatic Neurocritical Patients in ICU

NCT06993961 | Completed

• 1 other identifier: MD 265/2022
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to assess the role of ultrasound as a non-invasive method (bedside) to measure the rise of intracranial pressure by measuring the optic nerve sheath diameter in traumatic and nontraumatic neurocritical patients.

Conditions

Ultrasound; Optic Nerve Sheath Diameter; Non-Invasive; Intracranial Pressure; Neurocritical; Intensive Care Unit

Outcome Measures

Primary Outcomes (1)

• Intracranial Pressure

  Non-invasive bedside intracranial pressure (ICP) assessment via ultrasound (US) measurement of optic nerve sheath diameter (ONSD).

  24 hours post-procedure

Study Arms (1)

Study group

Patient with suspected high intracranial pressure (ICP) as determined by initial computed tomography (CT) brain.

Device: Ultrasound

Interventions

Ultrasound DEVICE

Ultrasound (US) measurement of optic nerve sheath diameter (ONSD) was performed.

Study group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This observational prospective trial involved 50 cases aged \>18 years old, both sexes, presenting with suspected high intracranial pressure (ICP). The study was conducted from August 2022 to July 2023 after approval from the Ethical Committee of Ain Shams University Hospitals, Cairo, Egypt.

You may qualify if:

• Age \>18 years old.
• Both sexes.
• Patients with suspected high intracranial pressure.

You may not qualify if:

• Cases suffering from eye disease or optic nerve problems (Glaucoma, optic Nerve Tumor, Neuritis, Orbital Fracture).
• Patients suffering from mental illness render them incapable of communication \& cooperation (For Example: Dementia and irritability).
• Any previous intensive care surgeries \& hyperthyroidism (due to exophthalmos)

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, 11591, Egypt

Location

MeSH Terms

Interventions

Ultrasonography

Intervention Hierarchy (Ancestors)

Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Study Record Dates

• First Submitted: May 20, 2025
• First Posted: May 29, 2025
• Study Start: August 1, 2022
• Primary Completion: July 1, 2023
• Study Completion: July 1, 2023
• Last Updated: May 29, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)