Comparing Two Eccentric Protocols on Muscle Damage
A Novel Eccentric Resistance Training Strategy to Maximize Exercise Induced Muscle Damage in Young Adults
1 other identifier
interventional
16
1 country
1
Brief Summary
The purpose of this study will be to test whether a new way of weight training is more effective than typical weight training. The investigators expect that this new way will cause more exercise-induced muscle damage, which helps people build bigger muscles. Another purpose of this study will be to explore perceptions of how muscle soreness impacts participant activities of daily living.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Mar 2023
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 8, 2023
CompletedFirst Submitted
Initial submission to the registry
March 9, 2023
CompletedFirst Posted
Study publicly available on registry
May 28, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2025
CompletedMay 28, 2025
November 1, 2024
2.2 years
March 9, 2023
May 19, 2025
Conditions
Outcome Measures
Primary Outcomes (4)
Muscle soreness 1
Visual analog scale as indirect indicator of muscle damage. Scale of 1-5. Higher score = more soreness
1 day
Muscle soreness 2
Visual analog scale as indirect indicator of muscle damage. Scale of 1-5. Higher score = more soreness
2 days
Muscle soreness 3
Visual analog scale as indirect indicator of muscle damage. Scale of 1-5. Higher score = more soreness
3 days
Maximal Voluntary Isometric Contraction Change
Change in MVIC will be used to indicated muscle damage.
pre-intervention, immediately after the intervention
Study Arms (2)
Fast Eccentric
EXPERIMENTALParticipants will perform fast eccentric resistance training
Slow eccentric
ACTIVE COMPARATORParticipants will perform slow eccentric resistance training
Interventions
Eligibility Criteria
You may qualify if:
- Sixteen young adults (ages 18-35) will be enrolled in this study.
- In order to be enrolled, they must have completed at least three months of resistance training in the past five years in order to minimize the learning effect and chance of injury.
You may not qualify if:
- Since regular resistance training reduces the primary outcomes, muscle damage and soreness, individuals who currently participate in chest press resistance training at least once per week will be excluded.
- Individuals who have musculoskeletal injuries in the shoulder, elbow or wrist that preclude pain-free resistance training, or who have underlying uncontrolled cardiovascular complications will also be excluded.
- Women who are pregnant, or may consider becoming pregnant over the subsequent 2 months, will be excluded
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
NYIT
Old Westbury, New York, 11568, United States
Study Officials
- PRINCIPAL INVESTIGATOR
Amerigo Rossi, Ed.D
New York Institute of Technology
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 9, 2023
First Posted
May 28, 2025
Study Start
March 8, 2023
Primary Completion
June 1, 2025
Study Completion
June 1, 2025
Last Updated
May 28, 2025
Record last verified: 2024-11
Data Sharing
- IPD Sharing
- Will not share