NCT06987344

Brief Summary

The goal of this study is to learn whether a 6-week lower-body training program using closed kinetic chain (CKC) exercises with slow, controlled movements (called "eccentric time under tension") can improve leg muscle strength and muscle-tendon viscoelastic properties in male university soccer players. The Main Questions Are:

  1. 1.Does this type of training improve knee strength?
  2. 2.Does it change the way muscles and tendons respond to movement or pressure?
  3. 3.Join one of two groups: one does the CKC training program, the other continues regular soccer training
  4. 4.Train twice a week for 6 weeks
  5. 5.Have their leg strength tested using special equipment
  6. 6.Have their muscle and tendon properties measured with a handheld device

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Jan 2025

Shorter than P25 for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 6, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 28, 2025

Completed
3 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

May 15, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 23, 2025

Completed
Last Updated

May 29, 2025

Status Verified

May 1, 2025

Enrollment Period

3 months

First QC Date

May 15, 2025

Last Update Submit

May 22, 2025

Conditions

Keywords

Exercise therapyMuscle strengthLower extremityTendons

Outcome Measures

Primary Outcomes (2)

  • Change from baseline in the rotational peak torque relative to body mass at 6 weeks

    Assessed using a Biodex® System 3 Pro isokinetic dynamometer (Shirley, NY, USA), with a validated accuracy of ±1%. Testing was performed at 60°/s angular velocity, a standard velocity for evaluating maximal voluntary muscle contraction. Participants were seated with their hips and knees at approximately 90° flexion. The dominant leg was tested and stabilized using straps at the trunk, thigh, and lower leg. Gravity correction was applied prior to testing. Following a 5-minute warm-up and 3 submaximal practice repetitions, each participant performed 3 maximal concentric repetitions of knee extension and flexion. The dominant leg was defined as the preferred leg for kicking, confirmed via observation of a standardized ball-kicking task.

    From enrollment to the end of closed kinetic chain training protocol at 6 weeks

  • Change from baseline in the rotational mean power at 6 weeks

    Assessed using a Biodex® System 3 Pro isokinetic dynamometer (Shirley, NY, USA), with a validated accuracy of ±1%. Testing was performed at 60°/s angular velocity, a standard velocity for evaluating maximal voluntary muscle contraction. Participants were seated with their hips and knees at approximately 90° flexion. The dominant leg was tested and stabilized using straps at the trunk, thigh, and lower leg. Gravity correction was applied prior to testing. Following a 5-minute warm-up and 3 submaximal practice repetitions, each participant performed 3 maximal concentric repetitions of knee extension and flexion. The dominant leg was defined as the preferred leg for kicking, confirmed via observation of a standardized ball-kicking task.

    From enrollment to the end of closed kinetic chain training protocol at 6 weeks

Secondary Outcomes (3)

  • Change from baseline in the agonist/antagonist strength ratio at 6 weeks

    From enrollment to the end of closed kinetic chain training protocol at 6 weeks

  • Change from Baseline in the muscle oscillation frequency at 6 weeks

    From enrollment to the end of closed kinetic chain training protocol at 6 weeks

  • Change from Baseline in the stiffness at 6 weeks

    From enrollment to the end of closed kinetic chain training protocol at 6 weeks

Study Arms (2)

Active Control Group

ACTIVE COMPARATOR

Maintained their customary daily activities and regular soccer training routines: Trained three times a week, two days were dedicated to functional and tactical on-field training, while the third day was reserved for a two-hour gym session focused on flexibility, muscular strength, and endurance development.

Other: Regular soccer training routines

Closed Kinetic Chain Group

EXPERIMENTAL

In addition to the same activities as the active cotrol group, participants performed five to seven different closed kinetic chain drills during the two days of field-based training, completing two to three sets per drill and eight to fourteen repetitions per set. The training volume underwent gradual increments over the course of every week. The total training volume for externally loaded CKC exercises was calculated by summing sets × repetitions × load (kg), yielding a cumulative volume of approximately 10,863 kg over 12 sessions. For exercises involving bodyweight or elastic resistance, training volume was estimated using time under tension (TUT), computed as the product of repetitions and eccentric phase duration. The cumulative TUT throughout the 6-week protocol amounted to 9,300 seconds (155 minutes) of eccentric loading.

Other: Field-based closed kinetic chain exercise with progressively increased time under tensionOther: Regular soccer training routines

Interventions

This intervention is uniquely characterized by the integration of field-based closed kinetic chain (CKC) exercises with a systematically increased eccentric time under tension (TUT), specifically tailored for university-level soccer players. Unlike conventional strength training protocols, which are often gym-based and rely on traditional resistance machines or free weights, this program emphasizes functional, sport-specific movement patterns performed on the field, enhancing ecological validity and transfer to soccer performance.

Closed Kinetic Chain Group

Trained three times a week: two days were dedicated to functional and tactical on-field training, while the third day was reserved for a two-hour gym session focused on flexibility, muscular strength, and endurance development.

Active Control GroupClosed Kinetic Chain Group

Eligibility Criteria

Age18 Years - 25 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Absence of any medical conditions that could compromise their ability to participate.
  • Active membership in their university's soccer team for a minimum of one year.

You may not qualify if:

  • Musculoskeletal injuries reported in the two months prior to the start of the study.
  • Surgical interventions involving the lower limbs within the past year.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Human Movement Analysis Laboratory

Viña del Mar, V región/Valparaíso, 2340000, Chile

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 15, 2025

First Posted

May 23, 2025

Study Start

January 6, 2025

Primary Completion

March 28, 2025

Study Completion

March 31, 2025

Last Updated

May 29, 2025

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Will be reported or made available upon reasonable request.

Locations