Retrolaminar Block Versus Erector Spinae Plane Block as Opioid-Free Anesthesia for Enhanced Recovery After Posterior Lumbar Discectomy

NCT06725680 | Completed

• 1 other identifier: 36264PR936/11/24
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to compare retrolaminar block and erector spine plane block as opioid-free anesthesia for enhanced recovery after posterior lumbar discectomy.

Conditions

Retrolaminar Block; Erector Spinae Plane Block; Opioid-Free Anesthesia; Enhanced Recovery; Lumbar Discectomy

Outcome Measures

Primary Outcomes (1)

• Time to the 1st rescue analgesia

  Time from end of surgery to first dose of morphine administrated.

  24 hours postoperatively

Secondary Outcomes (7)

• Recovery time

  Till first response to verbal command (Up to 1 hour)

• Time to discharge

  Till the Aldrete score is ≥9 (Up to 3 hours)

• Intraoperative fentanyl consumption

  Intraoperatively

• Total morphine consumption

  24 hours postoperatively

• Degree of pain

  24 hours postoperatively

Study Arms (2)

Retrolaminar block group

EXPERIMENTAL

Patients will receive retrolaminar block after the induction of general anesthesia.

Other: Retrolaminar block

Erector spinae plane block group

EXPERIMENTAL

Patients will receive erector spinae plane block after the induction of general anesthesia.

Other: Erector spinae plane block

Interventions

Retrolaminar block OTHER

Patients will receive retrolaminar block after the induction of general anesthesia.

Retrolaminar block group

Erector spinae plane block OTHER

Patients will receive erector spinae plane block after the induction of general anesthesia.

Erector spinae plane block group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age from 18 to 65 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-II.
• Undergoing elective posterior lumbar discectomy under general anesthesia.

You may not qualify if:

• Body mass index (BMI) \>35 kg/m2.
• Patients with disturbed mental status.
• Allergies to the drugs used in the study.
• Local infection at the puncture site.
• Cardiac insufficiency.
• Renal insufficiency.
• Coagulopathy.
• Chronic opioid use.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Study Record Dates

• First Submitted: December 5, 2024
• First Posted: December 10, 2024
• Study Start: December 11, 2024
• Primary Completion: October 7, 2025
• Study Completion: October 7, 2025
• Last Updated: November 19, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)