Scalp Care Efficacy Evaluation for Premium Scalp Revitalizing Essence
Evaluation of the Scalp Skin Care Effects of Premium Scalp Revitalizing Essence、Premium Scalp Revitalizing Essence 2、Premium Scalp Revitalizing Essence 3
1 other identifier
interventional
60
1 country
1
Brief Summary
The study aims to evaluate the efficacy of the Premium Scalp Revitalizing Essence on human scalp skin. A total of 60 healthy adults, aged 18 to 60, will be recruited and randomly assigned into five groups receiving different formulations. Participants will use the product once daily for 56 days, and their scalp conditions will be assessed through skin texture tests at multiple time points. Key parameters such as sebum content, overall hair loss, hair density, scalp condition, and hair length will be measured.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Apr 2025
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 8, 2025
CompletedFirst Submitted
Initial submission to the registry
May 20, 2025
CompletedFirst Posted
Study publicly available on registry
May 22, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 18, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
July 31, 2025
CompletedAugust 26, 2025
June 1, 2025
3 months
May 20, 2025
August 20, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (5)
Sebum Content
Assess oil levels on the scalp at standardized scalp sites (left, right, and vertex). Measured with C+K Multi Probe Adaptor MPA580 system using the Sebumeter® SM815 probe based on the grease spot photometry method with the sebum measurement cassette tape. The change in light transmission corresponds to the amount of sebum on the tape and is displayed on a scale from 0 to 350 units.
Assessment conducted every 14 days from Day 0 to Day 56 (including Day 0)
Hair length
Hair length (cm): Assessed with the ScalpX Intelligent Scalp Diagnostic System with digital microscopy at standardized scalp sites (left, right, and vertex).
Assessment conducted every 14 days from Day 0 to Day 56 (including Day 0)
Hair density
Hair density (number of hairs/cm-square): Assessed with the ScalpX Intelligent Scalp Diagnostic System with digital microscopy at standardized scalp sites (left, right, and vertex).
Assessment conducted every 14 days from Day 0 to Day 56 (including Day 0)
Hair thickness
Hair thickness (micrometers): Assessed with the ScalpX Intelligent Scalp Diagnostic System with digital microscopy at standardized scalp sites (left, right, and vertex).
Assessment conducted every 14 days from Day 0 to Day 56 (including Day 0)
Hair loss
Hair loss: Assessed by the standardized hair combing test by counting the number of hairs shed after the participants' hair was combed over a clean surface for 60 strokes.
Assessment conducted every 14 days from Day 0 to Day 56 (including Day 0)
Study Arms (5)
Group 1: Placebo control
PLACEBO COMPARATORBase formula without caffeine and panthenol
Group 2: Base formula only
EXPERIMENTALBase formula consisting of active ingredients caffeine and panthenol (vitamin B5).
Group 3: Base formula plus IGF-1 & FGF-7.
EXPERIMENTALBase formula plus insulin growth factor 1 (IGF-1) and fibroblast growth factor-7 (FGF-7)
Base formula plus Centella asiatica extracellular vesicles
EXPERIMENTALBase formula plus Centella asiatica extracellular vesicles
Group 5: Base formula plus Centella asiatica extracellular vesicles, IGF-1 & FGF-7.
EXPERIMENTALBase formula plus Centella asiatica extracellular vesicles, insulin growth factor-1 (IGF-1) and fibroblast growth factor-7 (FGF-7).
Interventions
Placebo control (base formula without caffeine and panthenol). Applied 1mL evenly to the scalp once daily after hair wash for 56 consecutive days.
Base formula consisting of active ingredients caffeine and panthenol. Applied 1mL evenly to the scalp once daily after hair wash for 56 consecutive days.
Base formula plus insulin growth factor 1 (IGF-1) and fibroblast growth factor-7 (FGF-7). Applied 1mL evenly to the scalp once daily after hair wash for 56 consecutive days.
Base formula plus Centella asiatica extracellular vesicles. Applied 1mL evenly to the scalp once daily after hair wash for 56 consecutive days.
Base formula plus Centella asiatica extracellular vesicles, insulin growth factor-1 (IGF-1) and fibroblast growth factor-7 (FGF-7). Applied 1mL evenly to the scalp once daily after hair wash for 56 consecutive days.
Eligibility Criteria
You may qualify if:
- Healthy adults of any gender from the age of 18 to 60 years (inclusive).
- Absence of chronic diseases, major illnesses, or allergies.
- Major illnesses include cancer, post-stroke disorders, paralysis, acute myocardial infarction, coro-nary artery bypass surgery, end-stage renal disease, and major organ transplant or hematopoietic stem cell transplant
You may not qualify if:
- Currently taking any medication or using any scalp care products
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hungkuang University
Taichung, 433304, Taiwan
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Vice President
Study Record Dates
First Submitted
May 20, 2025
First Posted
May 22, 2025
Study Start
April 8, 2025
Primary Completion
July 18, 2025
Study Completion
July 31, 2025
Last Updated
August 26, 2025
Record last verified: 2025-06