NCT07271199

Brief Summary

This study aims to evaluate the efficacy of the Premium Rejuvenation Eyelash Serum on eyelashes and the surrounding periorbital skin. A total of 30 healthy female participants, aged 18 to 60, will be recruited and randomly assigned to two groups to receive either test product or placebo at 1:1 ratio. Participants will apply the product twice daily for 56 days (8 weeks), with eyelash and periorbital skin conditions assessed at multiple time points using non-invasive measurements. Key parameters include eyelash density, eyelash length, and overall periorbital skin condition. At the end of the study (Day 56), participant will be asked to fill out a questionnaire on the usage of the intervention and self evaluation of eyelash condition.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2025

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

November 27, 2025

Completed
12 days until next milestone

First Posted

Study publicly available on registry

December 9, 2025

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 26, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 26, 2026

Completed
Last Updated

June 12, 2026

Status Verified

June 1, 2026

Enrollment Period

7 months

First QC Date

November 27, 2025

Last Update Submit

June 10, 2026

Conditions

Skin ConditionEyelash GrowthEyelashesSkin HealthHair Health

Keywords

EyelashEyelash healthSkin healthEyelash conditionHair healthProduct formulationGrowth factorsExtracellular vesicleGingerTurmeric

Outcome Measures

Primary Outcomes (2)

  • Eyelash density

    Assess eyelash density with Canfield VISIA® Skin Analysis system by assigning score from 1 (most dense, thick eyelashes) to 5 (least dense, thin eyelashes). Results will be expressed as percentage of change in eyelash density percentage relative to Day 0.

    Assessment conducted every 28 days from Day 0 to Day 56 (including Day 0 as baseline)

  • Eyelash length

    Assess eyelash length with Canfield VISIA® Skin Analysis system by assigning score from 1 (longest eyelashes) to 5 (shortest eyelashes). Results will be expressed as percentage of change in eyelash length percentage relative to Day 0

    Assessment conducted every 28 days from Day 0 to Day 56 (including Day 0 as baseline)

Secondary Outcomes (1)

  • Participant self-assessment

    Day 56 (End of the study period)

Study Arms (2)

Group 1: Placebo control

PLACEBO COMPARATOR

Base formula without active ingredient

Other: Placebo control

Group 2: Experimental formula

EXPERIMENTAL

Base formula with ginger (Zingiber officinale)-derived extracellular vesicle, turmeric (Curcuma longa)-derived extracellular vesicles, insulin growth factor-1 (IGF-1), and fibroblast growth factor-7 (FGF-7).

Other: Experimental formula

Interventions

Placebo controlOTHER

Placebo Control (Base Formula without active ingredients). After thoroughly cleansing the face and removing contact lenses (if applicable), apply 1 mL of the serum evenly to the base of the eyelashes. Allow the serum to absorb for a few minutes. Repeat application twice daily, in the morning and evening.

Group 1: Placebo control
Experimental formulaOTHER

Base formula with ginger (Zingiber officinale)-derived extracellular vesicle, turmeric (Curcuma longa)-derived extracellular vesicles, insulin growth factor-1 (IGF-1), and fibroblast growth factor-7 (FGF-7). After thoroughly cleansing the face and removing contact lenses (if applicable), apply 1 mL of the serum evenly to the base of the eyelashes. Allow the serum to absorb for a few minutes. Repeat this application twice daily, in the morning and evening.

Group 2: Experimental formula

Eligibility Criteria

Age18 Years - 60 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsFemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy female adults from the age of 18 to 60 years (inclusive).
  • Having symptoms of alopecia, baldness, or self-identified with hair thinning.
  • Absence of chronic diseases, major illnesses, or allergies.
  • Major illnesses include cancer, post-stroke disorders, paralysis, acute myocardial infarction, coronary artery bypass surgery, end-stage renal disease, and major organ transplant or hematopoietic stem cell transplant

You may not qualify if:

  • Currently taking any medication or using any eyelash care products.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hungkuang University

Taichung, 433304, Taiwan

Location

MeSH Terms

Conditions

Skin Diseases

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Vice President

Study Record Dates

First Submitted

November 27, 2025

First Posted

December 9, 2025

Study Start

November 1, 2025

Primary Completion

May 26, 2026

Study Completion

May 26, 2026

Last Updated

June 12, 2026

Record last verified: 2026-06

Locations

TW(1)