Management of Non Obstructive Azoospermia in Men

NCT06983626 | Completed DMC

• 1 other identifier: SVU MED URO016 2 22 5 401
• Study Type: interventional
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

this study predicts the factors of successful micro testicular sperm extraction in azoospermia patients in male infertility

Conditions

Azoospermia, Nonobstructive; Male Infertility

Outcome Measures

Primary Outcomes (1)

• Sperm Retrieval Success Rate and identification of Predictive Factors

  Determine which preoperative factors are significantly associated with successful sperm retrieval. These may include: Serum Follicle-Stimulating Hormone (FSH) Levels: Elevated FSH levels have been linked to reduced sperm retrieval success. And patient Age and testicular size to reach the best one to predict the success rate

  1st 1 year

Secondary Outcomes (1)

• Assess the success rates of ART procedures following sperm retrieval and complications

  2 years

Study Arms (1)

male infertility

ACTIVE COMPARATOR

azoospermia non obstructive type

Procedure: micro-dissection testicular sperm extraction

Interventions

micro-dissection testicular sperm extraction PROCEDURE

dissection of the seminefrous tubules under microscope to extract sperms

Also known as: TESE, TESA, PESA

male infertility

Eligibility Criteria

• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• redo Micro TESE

You may not qualify if:

• obstructive Azoospermia and bilateral congenital absent of vas

Sponsors & Collaborators

• South Valley University: lead

Study Sites (1)

Faculty of Medicine, South Valley University

Luxor, Qena Governorate, 83511, Egypt

Location

Related Links

• Azoospermia

MeSH Terms

Conditions

Infertility, Male; Azoospermia, Nonobstructive

Condition Hierarchy (Ancestors)

Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Infertility; Male Urogenital Diseases

Study Officials

• Gamal abdelhammid alsagheer, professour of urology, professour

  South Valley University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant lecturer of urology

Study Record Dates

• First Submitted: April 28, 2025
• First Posted: May 21, 2025
• Study Start: June 1, 2022
• Primary Completion: April 1, 2024
• Study Completion: April 1, 2025
• Last Updated: May 25, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: 2 years
• Access Criteria: urologist and andrologist

Locations

EG (1)