Change in Femoral Artery Doppler to Predict Successful Caudal Block

NCT06981780 | Completed

• 1 other identifier: Doppler and caudal block
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The ideal method to predict successful caudal block is still lacking. We hypothesized that the change in femoral artery Doppler indices could accurately predict successful caudal block

Conditions

Caudal Block

Keywords

Femoral artery Doppler; Pulsatility index; Caudal block

Outcome Measures

Primary Outcomes (1)

• Accuracy of Change in pulsatility index (PI) to predict successful caudal block

  The change in PI measured at baseline and 15 minutes after the block

  baseline and 15 minutes after the block

Secondary Outcomes (2)

• Accuracy of the change in resistive index to successful caudal block

  baseline and 15 minutes

• accuracy of change in waveform morphology to predict successful caudal block

  baseline and 15 minutes after the block

Study Arms (1)

Femoral artery Doppler

Each patient will be examined using femoral artery Doppler at 3 timepoints

Device: Femoral artery Doppler

Interventions

Femoral artery Doppler DEVICE

An experienced operator will conduct femoral artery examination for the change in Doppler indices namely pulsatility index, resisitive index, and waveform morphology

Femoral artery Doppler

Eligibility Criteria

• Age: 2 Years - 8 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Pediatric patients undergoing abdominal or lower limb surgery under general anesthesia combined with caudal block

You may qualify if:

• ASA1 or 2 lower abdominal or lower limb surgery

You may not qualify if:

• allergy to bupivacaine parental refusal coagulopathy inability to obtain adequate femoral artery views

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, Giza Governorate, 6890, Egypt

Location

Related Publications (5)

• Xu Z, Zhang J, Shen H, Zheng J. Assessment of pulse oximeter perfusion index in pediatric caudal block under basal ketamine anesthesia. ScientificWorldJournal. 2013 Sep 19;2013:183493. doi: 10.1155/2013/183493. eCollection 2013.

  PMID: 24174910 BACKGROUND

• Adolf Helmy M, Mansour M, Magdy Milad L, Mohammed Aboelregal E, Magdy Youssef M. Change in femoral artery pulsatility index as a novel predictor of post-spinal anesthesia hypotension in adult patients undergoing infra-umbilical surgeries: A prospective observational study. Anaesth Crit Care Pain Med. 2025 Apr;44(2):101482. doi: 10.1016/j.accpm.2025.101482. Epub 2025 Jan 21. No abstract available.

  PMID: 39848332 BACKGROUND

• Kim ES, Sharma AM, Scissons R, Dawson D, Eberhardt RT, Gerhard-Herman M, Hughes JP, Knight S, Marie Kupinski A, Mahe G, Neumyer M, Poe P, Shugart R, Wennberg P, Williams DM, Zierler RE. Interpretation of peripheral arterial and venous Doppler waveforms: A consensus statement from the Society for Vascular Medicine and Society for Vascular Ultrasound. Vasc Med. 2020 Oct;25(5):484-506. doi: 10.1177/1358863X20937665. Epub 2020 Jul 15.

  PMID: 32667274 BACKGROUND

• Boretsky KR, Camelo C, Waisel DB, Falciola V, Sullivan C, Brusseau E, Eastburn E, Gomez-Moraz A, Luckanavanich W. Confirmation of success rate of landmark-based caudal blockade in children using ultrasound: A prospective analysis. Paediatr Anaesth. 2020 Jun;30(6):671-675. doi: 10.1111/pan.13865.

  PMID: 32267040 BACKGROUND

• Kao SC, Lin CS. Caudal Epidural Block: An Updated Review of Anatomy and Techniques. Biomed Res Int. 2017;2017:9217145. doi: 10.1155/2017/9217145. Epub 2017 Feb 26.

  PMID: 28337460 BACKGROUND

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of anesthesia and critical care

Study Record Dates

• First Submitted: May 13, 2025
• First Posted: May 21, 2025
• Study Start: May 20, 2025
• Primary Completion: August 20, 2025
• Study Completion: August 21, 2025
• Last Updated: August 27, 2025

Record last verified: 2025-08

Locations

EG (1)