NCT06490666

Brief Summary

we aimed to evaluate the change in femoral artery pulsatility index as a predictor to post-spinal anesthesia hypotension

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
54

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 29, 2024

Completed
9 days until next milestone

First Posted

Study publicly available on registry

July 8, 2024

Completed
23 days until next milestone

Study Start

First participant enrolled

July 31, 2024

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 20, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 20, 2024

Completed
Last Updated

November 5, 2024

Status Verified

November 1, 2024

Enrollment Period

3 months

First QC Date

June 29, 2024

Last Update Submit

November 2, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • change in pulsatility index to predict post spinal anesthesia induced hypotension

    to measure PI before and after spinal anesthesia

    baseline and immediately after spinal anesthesia

Secondary Outcomes (2)

  • change in resistive index to predict post spinal anesthesia induced hypotension

    baseline and immediately after spinal anesthesia

  • change in waveform morphology to predict post spinal hypotension

    before and immediately after spinal anesthesia

Interventions

femoral artery pulse wave doppler to measure both pulsatility and resistive indices

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

adult patient undergoing spinal anesthesia for infra-umbilical surgeries

You may qualify if:

  • adult patient undergoing infra-umbilical surgeries.

You may not qualify if:

  • coagulopathy peripheral vascular disease contraindication to spinal anesthesia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cairo University

Cairo, Egypt

Location

Related Publications (3)

  • Hartmann B, Junger A, Klasen J, Benson M, Jost A, Banzhaf A, Hempelmann G. The incidence and risk factors for hypotension after spinal anesthesia induction: an analysis with automated data collection. Anesth Analg. 2002 Jun;94(6):1521-9, table of contents. doi: 10.1097/00000539-200206000-00027.

  • Wesselink EM, Kappen TH, Torn HM, Slooter AJC, van Klei WA. Intraoperative hypotension and the risk of postoperative adverse outcomes: a systematic review. Br J Anaesth. 2018 Oct;121(4):706-721. doi: 10.1016/j.bja.2018.04.036. Epub 2018 Jun 20.

  • Yu C, Gu J, Liao Z, Feng S. Prediction of spinal anesthesia-induced hypotension during elective cesarean section: a systematic review of prospective observational studies. Int J Obstet Anesth. 2021 Aug;47:103175. doi: 10.1016/j.ijoa.2021.103175. Epub 2021 May 1.

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

June 29, 2024

First Posted

July 8, 2024

Study Start

July 31, 2024

Primary Completion

October 20, 2024

Study Completion

October 20, 2024

Last Updated

November 5, 2024

Record last verified: 2024-11

Data Sharing

IPD Sharing
Will share

Locations