NCT06980181

Brief Summary

The study is conducted to assess whether the GMI or MT reduce the level of spasticity. Also to compare the level of independence in GMI and MT in the chronic stroke patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P50-P75 for not_applicable stroke

Timeline
Completed

Started Jun 2025

Shorter than P25 for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 12, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 20, 2025

Completed
26 days until next milestone

Study Start

First participant enrolled

June 15, 2025

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2025

Completed
16 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2025

Completed
Last Updated

July 10, 2025

Status Verified

July 1, 2025

Enrollment Period

Same day

First QC Date

May 12, 2025

Last Update Submit

July 6, 2025

Conditions

Stroke

Keywords

StrokeSpeech DisorderStroke RehabilitationHypertension

Outcome Measures

Primary Outcomes (1)

  • Modified Ashworth Scale

    Changes from baseline Modified Ashworth SCale is a clinical tool used to measure the spasticity.It comprises 4 grades.0 No increase in muscle tone, 1 Slight increase in muscle tone, manifested by a catch and release or by minimal resistance at the end of the range of motion (ROM), 1+ Slight increase in muscle tone, manifested by a catch, followed by minimal resistance throughout the remainder (less than half) of the ROM, 2 More marked increase in muscle tone through most of the ROM, but affected parts) easily moved, 3 Considerable increase in muscle tone, passive movement difficult, 4 Affected parts rigid in flexion or extension.

    4 weeks

Study Arms (2)

Graded Motor Imagery

EXPERIMENTAL

GMI uses visual cues and mental exercises to retain the brain in steps.

Other: Graded Motor Imagery

Mirror Therapy

ACTIVE COMPARATOR

Mirror Therapy uses a mirror to make the brain think the weak side is moving

Other: Mirror Therapy

Interventions

Graded Motor ImageryOTHER

Graded Motor Imagery typically 1 to 3 times per day for 5 to 10 minutes for each phase. No physical movement at first only cognitive task, mental rehearsal and visual motor.

Graded Motor Imagery
Mirror TherapyOTHER

Mirror Therapy typically involves 1 to 3 sessions per day for 10 to 15 minutes gradually increases as tolerated.Visual and motor training using a mirror placed at the midline.

Mirror Therapy

Eligibility Criteria

Age45 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age:45 to 65 years
  • First ever unilateral stroke and over 3 months since onset.
  • Both ischemic and hemorrhagic stroke individuals were included.

You may not qualify if:

  • Patients suffering from psychological problems.
  • Visual Impairments.
  • Fractures.
  • Any other Neurological disorder
  • Inflammatory joint diseases
  • Medical instability e.g Uncontrolled HTN
  • Any systemic disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Paraplegic Center

Peshawar, Khyber Pakhtunkhwa, 2500, Pakistan

Location

Related Publications (2)

  • Gandhi DB, Sterba A, Khatter H, Pandian JD. Mirror Therapy in Stroke Rehabilitation: Current Perspectives. Ther Clin Risk Manag. 2020 Feb 7;16:75-85. doi: 10.2147/TCRM.S206883. eCollection 2020.

    PMID: 32103968BACKGROUND

  • Gallanagh S, Quinn TJ, Alexander J, Walters MR. Physical activity in the prevention and treatment of stroke. ISRN Neurol. 2011;2011:953818. doi: 10.5402/2011/953818. Epub 2011 Oct 1.

    PMID: 22389836BACKGROUND

MeSH Terms

Conditions

StrokeSpeech DisordersHypertension

Interventions

Mirror Movement Therapy

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesLanguage DisordersCommunication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Physical Therapy ModalitiesRehabilitationTherapeutics

Study Officials

  • Usman Iqbal Janjua, Phd

    Elite College of Management Sciences

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Masking Details
Masking Description
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Model Description
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 12, 2025

First Posted

May 20, 2025

Study Start

June 15, 2025

Primary Completion

June 15, 2025

Study Completion

July 1, 2025

Last Updated

July 10, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)