NCT06978179

Brief Summary

This study aims to compare the efficacy of ultrasound-guided QL block and TAP block for postoperative pain management following lower abdominal surgeries.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at below P25 for not_applicable postoperative-pain

Timeline
Completed

Started Apr 2025

Shorter than P25 for not_applicable postoperative-pain

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 14, 2025

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

May 10, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 18, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 15, 2025

Completed
Last Updated

May 18, 2025

Status Verified

April 1, 2025

Enrollment Period

6 months

First QC Date

May 10, 2025

Last Update Submit

May 10, 2025

Conditions

Postoperative Pain

Outcome Measures

Primary Outcomes (1)

  • efficacy of ultrasound-guided QL block and TAP block for postoperative pain management following lower abdominal surgeries.

    Visual Analog Scale (VAS) at rest and at movement

    48 hours after operation

Study Arms (2)

US Guided QL Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients

ACTIVE COMPARATOR

Group ( 1 ) QLB "Type III": Patients will receive QLB performedwith20ml of diluted bupivacaine 0.25% on each side.

Procedure: Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients

US Guided TAP Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients

ACTIVE COMPARATOR

Group ( 2 ) TAP: Patients will receive TAP block performed with 20ml of diluted bupivacaine 0.25% on each side.

Procedure: Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients

Interventions

Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult PatientsPROCEDURE

Group ( 1 ) QLB "Type III": Patients will receive QLB performedwith20ml of diluted bupivacaine 0.25% on each side.

US Guided QL Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients
Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult PatientsPROCEDURE

Group ( 2 ) TAP: Patients will receive TAP block performed with 20ml of diluted bupivacaine 0.25% on each side.

US Guided TAP Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients aged from 18 to 65 years old.
  • American Society of Anesthesiologists (ASA) physical status I - II.
  • Patients scheduled for elective lower abdominal surgery.

You may not qualify if:

  • Patient refusal.
  • Patients with BMI (body mass index) \> 35 kg.m-2 , \[morbid obesity\].
  • Patients with significant neurological, psychatric or neuromascular disease.
  • Patients had local skin infection at the block injection site.
  • Patients who operated under epidural and patient-controlled analgesia \[PCA\].
  • Sensitivity to prescribed analgesia.
  • Coagulopathies or those who had uncontrolled chronic medical disease \[e.g. diabetes mellitus, hypertension, or cardiac diseases\].

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sohag University Hospital

Sohag, Egypt

RECRUITING

Related Publications (3)

  • Borglum J, Gogenur I, Bendtsen TF. Abdominal wall blocks in adults. Curr Opin Anaesthesiol. 2016 Oct;29(5):638-43. doi: 10.1097/ACO.0000000000000378.

    PMID: 27429253BACKGROUND

  • Wick EC, Grant MC, Wu CL. Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review. JAMA Surg. 2017 Jul 1;152(7):691-697. doi: 10.1001/jamasurg.2017.0898.

    PMID: 28564673BACKGROUND

  • Chen Q, Beal EW, Okunrintemi V, Cerier E, Paredes A, Sun S, Olsen G, Pawlik TM. The Association Between Patient Satisfaction and Patient-Reported Health Outcomes. J Patient Exp. 2019 Sep;6(3):201-209. doi: 10.1177/2374373518795414. Epub 2018 Aug 27.

    PMID: 31535008BACKGROUND

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Central Study Contacts

Ahmed M Abo El-Naga, Resident

CONTACT

01018434601ahmed_abuelnaga_post@med.sohag.edu.eg

Wesam A Abo El-Wafa, Professor

CONTACT

01002005802

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident, Anesthesiology, Surgical ICU and Pain Medicine, Faculty of Medicine, Sohag University

Study Record Dates

First Submitted

May 10, 2025

First Posted

May 18, 2025

Study Start

April 14, 2025

Primary Completion

October 15, 2025

Study Completion

October 15, 2025

Last Updated

May 18, 2025

Record last verified: 2025-04

Locations

EG(1)