is Generalized Aggressive Periodontitis an Endless Disease When Does it Stop

NCT06970691 | Completed

• 1 other identifier: 240418-89
• Study Type: observational
• Target: 92
• Locations: 1 country
• Sites: 1

Brief Summary

Background: Inquiring thoroughly and systematically for evidence supporting the mechanism, time span, onset, or ending events of generalized aggressive periodontitis. The aim of the current retrospective cross-sectional study was to set temporal boundaries of the generalized form of aggressive periodontitis based on eruption time of permanent teeth via panoramic radiographs. Methods: based on the Egyptian chronology, the primary outcome of the current retrospective study was to assess the correlation between the eruption sequence and the temporal borders of the disease as well as the prevalence of destructive events in accordance to the eruption schedule. The first affected tooth, the last affected tooth, the first unaffected tooth, the number of affected teeth, the presence of interrupted tooth all are factors that extracted from the panoramic radiographs.

Conditions

Aggressive Periodontitis, Generalized

Outcome Measures

Primary Outcomes (1)

• the radiographic eruption date of the first and the last affected teeth

  based on panoramic view of each patient, the radiographic eruption date of the mentioned teeth was determined.

  4 years

Secondary Outcomes (1)

• The radiographic status of the supporting structures of third molars

  4 years

Interventions

panoramic radiograph DIAGNOSTIC_TEST

Panoramic radiographs for aggressive periodontitis previously diagnosed cases were interpreted by single examiner (NY). The included radiographs had to fulfill the following; 1) sufficient image quality; 2) All teeth with the surrounding alveolar bone had to be clear enough to facilitate alveolar bone tracing; 3) Only pre-operative radiographs were enrolled (before the surgical management of bony defects).

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

All radiographic panoramic records of patients, who were previously clinically diagnosed as generalized aggressive periodontitis, were included. Fills with other radiographic records other than panoramic views were excluded. For this study, the enrolled patients' age was selected ≥ 18 years of both genders. Radiographic evidence of bony defects was compulsory for inclusion.

You may qualify if:

• patients with generalized ggressive perioodntitis only
• Panoramic view is a must
• Patient age ≥ 18 years
• both genders were enrolled

You may not qualify if:

• patients who did not have panoramic radiograph in their files
• Patients less than 18 years are not included

Sponsors & Collaborators

• Rasha Wagih: lead

Study Sites (1)

Faculty of Dentistry

Cairo, Egypt

Location

MeSH Terms

Conditions

Aggressive Periodontitis

Interventions

Radiography, Panoramic

Condition Hierarchy (Ancestors)

Periodontitis; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Radiography, Dental; Radiography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Diagnosis, Oral; Dentistry

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Head of periodontology department

Study Record Dates

• First Submitted: March 17, 2025
• First Posted: May 14, 2025
• Study Start: January 16, 2020
• Primary Completion: December 20, 2024
• Study Completion: December 20, 2024
• Last Updated: May 14, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)