NCT06966531

Brief Summary

This study aims to determine the prevalence of myocarditis among patients suspected of having myocardial infarction with non-obstructive coronary arteries (MINOCA) and to analyze its clinical characteristics, diagnostic markers .

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
148

participants targeted

Target at P50-P75 for all trials

Timeline
11mo left

Started May 2025

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress53%
May 2025Apr 2027

First Submitted

Initial submission to the registry

May 4, 2025

Completed
1 day until next milestone

Study Start

First participant enrolled

May 5, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

May 12, 2025

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2027

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2027

Last Updated

May 12, 2025

Status Verified

May 1, 2025

Enrollment Period

1.8 years

First QC Date

May 4, 2025

Last Update Submit

May 4, 2025

Conditions

Keywords

MyocarditisMINOCANormal coronary angiography

Outcome Measures

Primary Outcomes (1)

  • Prevalence of myocarditis in patients presenting with MINOCA, as diagnosed by CMR.

    Studying The incidence of myocarditis in MINOCA patients

    1 years

Study Arms (1)

MINOCA

Acute Myocardial infarction patient with non obstructive coronary arteries

Procedure: Coronary angiography

Interventions

distinguish between true MI with significant lesion and MINOCA with insignificant lesions (less than 50%)

MINOCA

Eligibility Criteria

Age17 Years - 80 Years
Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Study Population Description Myocardial infarction patients who were underwent PPCI and the coronary angiography showing insignificant lesions (stenosis less than 50% )

You may qualify if:

  • All patients; diagnosed with myocardial infarction with nonobstructive coronary arteries (MINOCA)
  • clinical symptoms
  • ECG : ischemic changes with or without ST segment elevation
  • Echocardiograpy : segmental wall motion abnormalities (SWMA)
  • positive cardiac enzymes
  • Coronary angiography: insignificant lesions ,the absence of culprit obstructive coronary artery disease (epicardial coronary artery stenosis ≥50%)

You may not qualify if:

  • Significant coronary artery disease (\>50% stenosis) on angiography.
  • Prior history of myocarditis or cardiomyopathy.
  • Contraindications to CMR (e.g., pacemakers, severe renal dysfunction).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Links

MeSH Terms

Conditions

MyocarditisMINOCA

Condition Hierarchy (Ancestors)

CardiomyopathiesHeart DiseasesCardiovascular DiseasesMyocardial InfarctionMyocardial IschemiaVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Officials

  • Ayman khairy Mohamed Hassan

    Cardiology department

    PRINCIPAL INVESTIGATOR
  • Khaled Mohamed Abdullah Mohamed

    Cardiology department

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ahmed Gamal Thabit Mohamed

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident , department of Cardiology،Principal Investigator

Study Record Dates

First Submitted

May 4, 2025

First Posted

May 12, 2025

Study Start

May 5, 2025

Primary Completion (Estimated)

March 1, 2027

Study Completion (Estimated)

April 1, 2027

Last Updated

May 12, 2025

Record last verified: 2025-05