Acute Coronary Syndrome in Patients With COVID-19

NCT05732597 | Completed DMC

• 1 other identifier: 1
• Study Type: observational
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to find a clinical or laboratory parameter, that would help in distinguishing between COVID-19 patients with myocardial infarction (MI), who have an infarct-related artery (IRA) and therefore, require immediate revascularization, and those, who have no IRA.

Conditions

Myocardial Infarction; Acute Coronary Syndrome; COVID-19; Myocardium; Injury

Keywords

COVID-19; Coronavirus; Acute coronary syndrome; Troponin

Outcome Measures

Primary Outcomes (1)

• to find a clinical or laboratory parameter, that would help in distinguishing between COVID-19 patients with MI and IRA and those, who have no IRA

  During the whole study

Study Arms (2)

Patients with ACS and no IRA

Patients with acute coronary syndrome (ACS) during a COVID-19 infection, who after undergoing coronary angiography - no infarct-related artery (IRA) is found

Procedure: Coronary angiography

Patients with ACS and IRA

Patients with acute coronary syndrome (ACS) during a COVID-19 infection, who after undergoing coronary angiography - an infarct-related artery (IRA) is found

Procedure: Coronary angiography

Interventions

Coronary angiography PROCEDURE

A coronary angiogram is a procedure that uses X-ray imaging to see the patient's blood vessels of the heart. The test is generally done to see if there's a restriction in blood flow going to the heart.

Patients with ACS and IRA; Patients with ACS and no IRA

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Every patient above 18 years old with ACS and COVID-19 infection

You may qualify if:

• Acute coronary syndrome (ACS)
• COVID-19 infection

You may not qualify if:

• No combination of ACS and COVID-19 infection

Sponsors & Collaborators

• Bulgarian Cardiac Institute: lead

Study Sites (1)

Heart and brain center of clinical excellence, University hospita, Pleven, Bulgaria

Pleven, 5800, Bulgaria

Location

MeSH Terms

Conditions

Myocardial Infarction; Acute Coronary Syndrome; COVID-19; Wounds and Injuries; Coronavirus Infections

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 16, 2023
• First Posted: February 17, 2023
• Study Start: November 1, 2020
• Primary Completion: February 27, 2022
• Study Completion: February 27, 2022
• Last Updated: August 6, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

BU (1)