NCT06958055

Brief Summary

evaluate the effect of implant retained mandibular overdenture on vallecular bolus aggregation during chewing and subsequent swallowing of solid food consistency.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2024

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 26, 2024

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 26, 2024

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 27, 2025

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

April 27, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 6, 2025

Completed
Last Updated

May 6, 2025

Status Verified

April 1, 2025

Enrollment Period

9 months

First QC Date

April 27, 2025

Last Update Submit

April 27, 2025

Conditions

Keywords

vallecular aggregationswallowingsolid foodimplant overdenture

Outcome Measures

Primary Outcomes (1)

  • swallowing evaluation

    videofluroscopy evaluation for swallowing function

    after 3 months of denture and overdenture insertion

Study Arms (3)

group I : complete edentulous patients

PLACEBO COMPARATOR

videofluroscopy for completely edentulous patients

Radiation: videofluroscopy evaluation of swallowing function

group II: Conventional complete denture

ACTIVE COMPARATOR

complete denture construction for edentulous patient and videofluroscopy evaluation

Radiation: videofluroscopy evaluation of swallowing function

group III: Implant overdentutres

ACTIVE COMPARATOR

construction of implant overdenture and videofluroscopy evaluation

Radiation: videofluroscopy evaluation of swallowing function

Interventions

Videofluoroscopy swallowing evaluation was done using solid food bolus at three different oral conditions: Without dentures (WOD), with the conventional complete denture (CDs) and with mandibular implant retained overdenture (IODs).

group I : complete edentulous patientsgroup II: Conventional complete denturegroup III: Implant overdentutres

Eligibility Criteria

Age60 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age \>60 year.
  • Class I maxilla-mandibular relation;
  • Available inter-arch space.
  • adequate bone quality and quality in the mandibular anterior alveolar ridge (inter-foraminal area).

You may not qualify if:

  • Subjects with physical or cognitive limitations,
  • Neurodegenerative disorders that could influence their swallowing function,
  • Parafunctional habits,
  • Smokers,
  • Signs or symptoms of temporomandibular disorders,
  • Osteoporosis,
  • Uncontrolled systemic diseases,
  • Previously undergone radiotherapy or laryngeal surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

faculty of dentistry, mansoura university Mansoura, Egypt,

Al Mansurah, 35516, Egypt

Location

Related Publications (1)

  • Ibrahim AM, Elgamal M, Abdel-Khalek EA. Hyoid displacement during swallowing function for completely edentulous subjects rehabilitated with mandibular implant retained overdenture. BMC Oral Health. 2024 Aug 8;24(1):914. doi: 10.1186/s12903-024-04616-9.

MeSH Terms

Conditions

Prosthesis Failure

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • abdallah M Ibrahim, PhD

    Mansoura university, Faculty of dentistry, prosthodontics department

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 27, 2025

First Posted

May 6, 2025

Study Start

January 26, 2024

Primary Completion

October 26, 2024

Study Completion

March 27, 2025

Last Updated

May 6, 2025

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will not share

Locations