Effects of Enteral Nutrition Content on Disease Progression in Sepsis Patients

NCT06943326 | Recruiting

• 1 other identifier: Inonu-NAD-HT-02
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to investigate the effects of enteral nutrition content on disease progression in sepsis patients.

Conditions

Sepsis; Nutritional Deficiency

Keywords

sepsis; intensive care; nutrition

Outcome Measures

Primary Outcomes (12)

• Change in Serum Glucose Level

  Change in fasting blood glucose level (mg/dL) from baseline to Day 7.

  Baseline and Day 7

• Change in Serum Albumin Level

  Change in serum albumin concentration (g/dL) from baseline to Day 7.

  Baseline and Day 7

• Change in Serum C-Reactive Protein (CRP) Level

  Change in serum CRP level (mg/L) from baseline to Day 7.

  Baseline and Day 7

• Change in Hemoglobin Level

  Change in hemoglobin concentration (g/dL) from baseline to Day 7.

  Baseline and Day 7

• Change in Serum Urea Level

  Change in serum urea concentration (g/dL) from baseline to Day 7.

  Baseline and Day 7

• Change in Serum Creatinine Level

  Change in serum creatinine concentration (g/dL) from baseline to Day 7.

  Baseline and Day 7

• Change in Absolute Lymphocyte Count

  Change in absolute lymphocyte count () from baseline to Day 7.

  Baseline and Day 7

• Change in Total Leukocyte Count

  Change in total leukocyte count (10\^3/µL) from baseline to Day 7.

  Baseline and Day 7

• Change in Monocyte Count

  Change in absolute monocyte count (10\^3/µL) from baseline to Day 7.

  Baseline and Day 7

• Change in Neutrophil Count

  Change in absolute neutrophil count (10\^3/µL) from baseline to Day 7.

  Baseline and Day 7

• Change in Eosinophil Count

  Change in absolute eosinophil count (10\^3/µL) from baseline to Day 7.

  Baseline and Day 7

• Change in Basophil Count

  Change in absolute basophil count (10\^3/µL) from baseline to Day 7.

  Baseline and Day 7

Interventions

nutrition monitoring OTHER

There is no investigator intervention in the study. Patients' nutrition is recorded for one week from the beginning of the study.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with sepsis who were older than 18 years and receiving enteral nutrition and receiving treatment in the Intensive Care Unit of Mehmet Akif Inan Training and Research Hospital were included.

You may qualify if:

• Being diagnosed with sepsis and being able to receive enteral nutrition 24 hours after starting treatment in the intensive care unit

You may not qualify if:

• chronic liver disease, chronic renal failure, active cancer or parenteral nutrition

Sponsors & Collaborators

• Inonu University: lead

Study Sites (1)

Mehmet Akif Inan Training and Research Hospital

Sanliurfa, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Sepsis; Malnutrition

Condition Hierarchy (Ancestors)

Infections; Systemic Inflammatory Response Syndrome; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Nutrition Disorders; Nutritional and Metabolic Diseases

Central Study Contacts

HAKAN TOĞUÇ

CONTACT

+905073625100; hakan.toguc@inonu.edu.tr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Week
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: April 8, 2025
• First Posted: April 24, 2025
• Study Start: November 1, 2024
• Primary Completion: January 1, 2025
• Study Completion: May 1, 2025
• Last Updated: April 24, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)