Host Dysregulation-Driven Sepsis Prediction Model
Construction and Validation of a Sepsis Prediction Model Based on Dysregulation of Host Response
1 other identifier
observational
1,000
1 country
2
Brief Summary
The aim of this study is to identify risk factors associated with sepsis and to construct a predictive model for sepsis. This will provide an objective theoretical and empirical foundation for the diagnosis, assessment, and management of sepsis in our country.The primary questions addressed are: What are the risk factors for the development of sepsis? How do we improve the prognosis of sepsis?
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2024
Shorter than P25 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 14, 2024
CompletedFirst Posted
Study publicly available on registry
July 26, 2024
CompletedStudy Start
First participant enrolled
September 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 13, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
October 17, 2024
CompletedOctober 31, 2024
October 1, 2024
1 month
July 14, 2024
October 29, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Sepsis
A rapid increase of 2 or more points points in the Sequential Organ Failure Assessment (SOFA) score after patient infection.SOFA score, which ranges from a minimum of 2 to a maximum of 15, indicates a worse outcome with higher scores.
3 months
Study Arms (2)
Sepsis Group
Non-Sepsis Group
Interventions
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Eligibility Criteria
Patients with Infection or Suspected Infection
You may qualify if:
- Patients with Infection or Suspected Infection
You may not qualify if:
- Patients with Autoimmune Diseases
- Pregnant Women
- Patients with Advanced-Stage Cancer and Systemic Metastasis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Xiue Ye
Wenzhou, Zhejiang, 325000, China
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University,
Wenzhou, Zhejiang, 325027, China
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 14, 2024
First Posted
July 26, 2024
Study Start
September 1, 2024
Primary Completion
October 13, 2024
Study Completion
October 17, 2024
Last Updated
October 31, 2024
Record last verified: 2024-10