NCT06913998

Brief Summary

The study will include participants who were diagnosed with inflammatory disease and followed up at National Taiwan University Children's Hospital. The investigators will check the NUDT15 gene test, if the participant agrees to do an additional blood test. The result of the gene test will be analyzed and compared with other clinical data.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
65

participants targeted

Target at P25-P50 for all trials

Timeline
5mo left

Started Dec 2023

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress87%
Dec 2023Nov 2026

Study Start

First participant enrolled

December 27, 2023

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

March 30, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 6, 2025

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2026

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2026

Expected
Last Updated

April 8, 2025

Status Verified

November 1, 2024

Enrollment Period

2 years

First QC Date

March 30, 2025

Last Update Submit

April 6, 2025

Conditions

Inflammatory Bowel DiseasesNeutropeniaNudt15 Deficiency

Outcome Measures

Primary Outcomes (1)

  • Neutropenia

    Neutropenia is defined as absolute neutrophil count \<1500/microL, and severe neutropenia is defined as absolute neutrophil count \<500/microL.

    2 years

Eligibility Criteria

Age1 Year - 25 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

The study included participants who are diagnosed with inflammatory bowel disease at National Taiwan University Children's Hospital and agree to have blood test for NUDT15 gene evaluation.

You may qualify if:

  • Participants who are diagnosed with inflammatory bowel disease.

You may not qualify if:

  • Participants who refused to have blood test for NUDT15 gene evaluation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, 100, Taiwan

RECRUITING

MeSH Terms

Conditions

Inflammatory Bowel DiseasesNeutropenia

Condition Hierarchy (Ancestors)

GastroenteritisGastrointestinal DiseasesDigestive System DiseasesIntestinal DiseasesAgranulocytosisLeukopeniaCytopeniaHematologic DiseasesHemic and Lymphatic DiseasesLeukocyte Disorders

Central Study Contacts

Wei-Ting Chen, MD

CONTACT

+886-2-2312-3456DBE98@tepch.gov.tw

Jia-Feng Wu, MD, PhD

CONTACT

+886-2-2312-3456wjf@ntu.edu.tw

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
2 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 30, 2025

First Posted

April 6, 2025

Study Start

December 27, 2023

Primary Completion

January 1, 2026

Study Completion (Estimated)

November 1, 2026

Last Updated

April 8, 2025

Record last verified: 2024-11

Locations

TW(1)