Study on Lipid Profile Changes in Plasma and Intestinal Mucosa of Patients With Inflammatory Bowel Disease

NCT06680076 | Not Yet Recruiting DMC

• 1 other identifier: Harbin Medical University
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to demonstrate the characteristic lipid profile changes in patients with inflammatory bowel disease.

Conditions

Inflammatory Bowel Diseases

Keywords

IBD; lipid metabolism; activity

Outcome Measures

Primary Outcomes (2)

• Differential lipid composition between disease and healthy groups

  Differences in lipid composition between disease and healthy groups.

  14 weeks

• Differences in lipid composition between active and remission disease

  Differences in lipid composition between active and remission disease

  14 weeks

Study Arms (2)

Disease group

Patients who have inflammation bowel disease.

Health group

Healthy people who volunteered to participate.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy volunteers and patients who have inflammation bowel disease.

You may qualify if:

• Patients with inflammatory bowel disease; aged 18-80 years; all cases agreed to participate in the study.
• Healthy volunteers who agreed to participate in the study.

You may not qualify if:

• Patients with severe heart disease; patients with severe kidney disease; patients with low blood pressure; patients with severe infections such as sepsis or pneumonia; patients who have used immunosuppressants such as 6-mercaptopurine, imidazole thiopurine, and cyclosporine within a short period, and women during pregnancy; patients who are post-colon resected; patients who disagreed to participate in the study.

Sponsors & Collaborators

• First Affiliated Hospital of Harbin Medical University: lead

Study Sites (1)

Carol

Harbin, Heilongjiang, 150001, China

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Colon tissue and plasma

MeSH Terms

Conditions

Inflammatory Bowel Diseases; Motor Activity

Condition Hierarchy (Ancestors)

Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Intestinal Diseases; Behavior

Study Officials

• Hongyu D Xu, PHD

  Harbin Medical University

  STUDY DIRECTOR

Central Study Contacts

Huichao Zhang, MD

CONTACT

13945003159; zhanghuichao0609@163.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief of the GI department

Study Record Dates

• First Submitted: November 6, 2024
• First Posted: November 8, 2024
• Study Start: December 1, 2024
• Primary Completion: February 25, 2025
• Study Completion: March 30, 2025
• Last Updated: December 12, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)