NCT06907303|Enrolling By Invitation
RNA Assays for Endometriosis Detection and Diagnosis
RNA-EndoDx
Development and Evaluation of RNA-based Markers for Detecting and Diagnosing Endometriosis
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RNA-EndoDx
Development and Evaluation of RNA-based Markers for Detecting and Diagnosing Endometriosis
Sponsor study identifier
observational
400
2 countries
2
Study Start
January 1, 2024
Actual (reported)Primary Completion
August 31, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Endometriosis is a common disease that affects up to 10% of women of reproductive age. Diagnosis, however, is typically delayed (up to 12 years) and is usually made after surgery. A key unmet need therefore is an accurate biomarker that can be used to detect the disease early. This study is a prospective trial to identify candidate mRNA-markers which can be used to aid in the diagnosis of this disease. It is a discovery/validation study that will identify and confirm a gene expression panel that is specific for endometriosis and provides a non-invasive tool for future use.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1, 2024
Actual (reported)March 25, 2025
Actual (reported)April 2, 2025
Actual (reported)August 31, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Develop a gene signature that detects endometriosis
Gene expression levels in samples from endometriosis subjects and controls
12-18 months
Assess the diagnostic utility of the gene signature to differentiate between endometriosis and controls
6 months
Women with suspected endometriosis undergoing laparoscopy to provide tissue for pathological diagnosis of the disease.
Women undergoing surgery for benign cervical disease.
PCR assay for Endometriosis diagnosis
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Women with high suspicion of endometriosis and women undergoing surgery for benign cervical disease.
Wren Laboratories
Branford, Connecticut, 06405, United States
University of Cape Town
Cape Town, South Africa
Tissue, blood, saliva
First Submitted
March 25, 2025
First Posted
April 2, 2025
Study Start
January 1, 2024
Actual (reported)Primary Completion
August 31, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Blood and Tissue Markers for Improving Diagnosis and Prognosis of Endometriosis. (ENDOBIO)
Effect of Yoga on Pelvic Pain and Quality of Life in Endometriosis
Contact the study team to confirm eligibility.
Study Completion
December 31, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
April 2, 2025
Record last verified: 2025-03
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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