NCT06905041

Brief Summary

To assess the impact of preoperative anemia on postoperative outcomes in patients undergoing liver resection

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
728

participants targeted

Target at P75+ for all trials

Timeline
9mo left

Started Mar 2025

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress60%
Mar 2025Jan 2027

First Submitted

Initial submission to the registry

March 25, 2025

Completed
6 days until next milestone

Study Start

First participant enrolled

March 31, 2025

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 1, 2025

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2027

Last Updated

April 1, 2025

Status Verified

March 1, 2025

Enrollment Period

1.8 years

First QC Date

March 25, 2025

Last Update Submit

March 25, 2025

Conditions

Liver ResectionAnemiaPostoperative Mortality and Morbidity

Keywords

Preoperative anemia, liver resection, posteoperative complication

Outcome Measures

Primary Outcomes (1)

  • Postoperative 30-day morbidity rate

    • To determine whether preoperative anemia is associated with increased risk of postoperative 30-day morbidity in patients undergoing liver resection.

    From enrollment to the postoperative day 30

Secondary Outcomes (1)

  • Allogenic blood transfusion, comprehensive complication index, postoperative outcomes, and mortality rate

    From enrollment to the postoperative day 30

Study Arms (2)

Anemia group

The patients who had preoperative anemia (hemoglobin levels \< 12 g/dL in female and \< 13 g/dL in male) before liver resection

No anemia group

The patients who did not have preoperative anemia before liver resection.

Eligibility Criteria

Age20 Years - 75 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who underwent elective liver resection in setting hospital during January, 2006 to December, 2024

You may qualify if:

  • All genders, age 20 to 75 years old who undergoing elective liver resection
  • American Society of Anesthesiologists (ASA) physical status classification of I-III

You may not qualify if:

  • Living donor liver resection
  • Withdrawal criteria:
  • Unresectable tumor
  • Cardiac arrest during operation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Anemia

Condition Hierarchy (Ancestors)

Hematologic DiseasesHemic and Lymphatic Diseases

Study Officials

  • Warangkana Lapisatepun, MD. PhD.

    Chiang Mai University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Warangkana Lapisatepun, MD. PhD.

CONTACT

+66910688716warangkana.c@cmu.ac.th

Worakitti Lapisatepun, MD.

CONTACT

0910688761worakitti.l@cmu.ac.th

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Faculty of Medicine, Chiang Mai University

Study Record Dates

First Submitted

March 25, 2025

First Posted

April 1, 2025

Study Start

March 31, 2025

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

January 31, 2027

Last Updated

April 1, 2025

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will not share