Combining Transcranial Direct Current Stimulation and Core Stability Exercise on Trunk in Stroke Patient

NCT06882213 | Enrolling By Invitation DMC

• 1 other identifier: Transcranial Direct Current
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

To evaluate the effects of the combining transcranial direct current stimulation with core stability exercises on trunk performance in poststroke hemiparetic patients, the secondary outcome is to evaluate the balance and the functional performance of the participants.

Conditions

Stroke

Outcome Measures

Primary Outcomes (2)

• Trunk Impairment Scale (TIS).

  trunk performance will be assessed by Trunk Impairment Scale (TIS).

  up to 8 weeks

• Berg Balance Scale

  Balance will be assessed by berg balance scale, the balance score ranges from 0 to 56, with lower scores indicating increased risk of balance loss and higher scores indicating improved functional mobility. Time up and go test (TUG)n Score \< 10 seconds = normal \< 20 seconds = good mobility; can walk outside alone; does not require a walking aid \< 30 seconds = walking and balance problems; cannot walk outside alone; requires walking aid

  up to 8 weeks

Study Arms (2)

Study Group

ACTIVE COMPARATOR

will receive simultaneously a combination of transcranial direct current stimulation combined with core stability exercise.

Other: transcranial direct current stimulation; Other: core stability exercise.

Control group

ACTIVE COMPARATOR

will receive core stability exercise.

Other: core stability exercise.

Interventions

transcranial direct current stimulation OTHER

transcranial direct current stimulation

Study Group

core stability exercise. OTHER

core stability exercise.

Control group; Study Group

Eligibility Criteria

• Age: 55 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients will be included if they are ≥ 55 years old of both sex, had a first-time right or left stroke within the preceding six months that damaged the cerebral cortex verified by (computed tomography or MRI report, neurological examination, and medical chart).
• Patients can stand and walk independently.
• Modified Ashworth Scale (MAS) of upper limb muscle ≤ 1+.
• All the patients received a conventional physiotherapy program in the acute stage and post-discharge from the hospital.
• None of the patients participated in any other study or placebo

You may not qualify if:

• Patients with neurological or orthopedic problems, paralysis neglect, behavioral abnormalities, dementia any shoulder dysfunction before or post-stroke (dislocation or subluxation), or those who using upper limb splints.
• Recurrent strokes or hemiparesis due to other neurological causes rather than stroke eg .(Brain tumor).
• Obesity (BMI ≥ 30 kg/m2).

Sponsors & Collaborators

• Beni-Suef University: lead

Study Sites (1)

Beni suef hospital

Banī Suwayf, 62511, Egypt

Location

MeSH Terms

Conditions

Stroke

Interventions

Transcranial Direct Current Stimulation

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Electric Stimulation Therapy; Therapeutics; Convulsive Therapy; Psychiatric Somatic Therapies; Behavioral Disciplines and Activities; Electroshock; Psychological Techniques

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Physical therapy

Study Record Dates

• First Submitted: March 12, 2025
• First Posted: March 18, 2025
• Study Start: March 29, 2025
• Primary Completion: March 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: February 17, 2026

Record last verified: 2025-03

Locations

EG (1)