The Effect of Paravertebral Block on Recovery After CABG Surgery
The Effect of Ultrasound-Guided Bilateral Single-Shot Paravertebral Block on Recovery After Coronary Artery Bypass Graft Surgery
1 other identifier
interventional
120
0 countries
N/A
Brief Summary
The study aims to evaluate the analgesic efficacy of paravertebral block, mobilization speed, respiratory functions, and complication rates in patients who have undergone cardiac surgery and are monitored in the intensive care unit during the postoperative period.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Mar 2025
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 12, 2025
CompletedFirst Posted
Study publicly available on registry
March 18, 2025
CompletedStudy Start
First participant enrolled
March 24, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 25, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
August 15, 2025
CompletedMarch 20, 2025
March 1, 2025
4 months
March 12, 2025
March 18, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Quality of Recovery -15 (QoR-15) score
The QoR-15 is a clinically acceptable and feasible patient-centred outcome measure after surgery. The score demonstrated good validity, reliability and responsiveness. The score ranges from 0 to 150. O refers to the worst recovery and 150 refers to best recovery.
Postoperative 24th hours
Secondary Outcomes (3)
Visual Analog scale (VAS) score
Postoperative 2nd, 4th, 6th, 12th and 24th hours
Opioid consumption
Postoperative 24th hours
Extubation time
Time frame from the end of the surgery to extubation
Study Arms (2)
Control group
NO INTERVENTIONNo intervention planned for control group. Patients in the control group will receive a standard analgesia protocol.
Block group
EXPERIMENTALUSG guided single-shot paravertebral block planned for block group
Interventions
A single-dose bilateral paravertebral block will be administered under ultrasound guidance before the induction of general anesthesia. The block will be performed at an appropriate thoracic level using 20 mL of 0.25% bupivacaine as the local anesthetic.
Eligibility Criteria
You may qualify if:
- Patients aged 18 and older scheduled for elective coronary artery bypass graft surgery with median sternotomy
You may not qualify if:
- Contraindications to neuroaxial block ( coagulopathy, infection at the injection site, allergy to local anesthetics..)
- Emergency surgeries
- severe back deformities
- Chronic pain
- refusal to participate
- CABG without sternotomy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- INVESTIGATOR, OUTCOMES ASSESSOR
- Masking Details
- The researchers who performed the blocks did not participate in the outcome assessments, and similarly, the researcher evaluating the outcomes was not involved in the paravertebral block procedures.
- Purpose
- SCREENING
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
March 12, 2025
First Posted
March 18, 2025
Study Start
March 24, 2025
Primary Completion
July 25, 2025
Study Completion
August 15, 2025
Last Updated
March 20, 2025
Record last verified: 2025-03