Single Anastomosis Sleeve Jejunal Bypass Versus One Anastomosis Gastric Bypass in Management of Morbid Obese Patients: A Comparative Study

NCT06857097 | Not Yet Recruiting DMC

• 1 other identifier: Soh-Med-25-2-4MD
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This study was conducted aiming to assess the efficacy of SASJ bypass as a novel bariatric procedure in terms of operative time, weight loss, complications and effect on comorbidities compared to the outcomes of OAGB within two years after operation.

Conditions

Single Anastomosis Sleeve Jejunal Bypass

Outcome Measures

Primary Outcomes (1)

• Weight loss parameters

  2 years

Study Arms (2)

single anastomosis sleeve jejunal bypass group

ACTIVE COMPARATOR

Procedure: single anastomosis sleeve jejunal bypass

one anastomosis gastric bypass

ACTIVE COMPARATOR

dissection started just distal to the crows' foot till reaching the lesser sac. A long narrow gastric pouch was created by the endostapler. After that, a longitudinal gastrojejunostomy (4-cm wide) was created at 200 cm distal to the Treitz ligament as the SASJ grou p.

Procedure: One anastomosis gastric bypass

Interventions

single anastomosis sleeve jejunal bypass PROCEDURE

sleeve was created starting devascularization of greater gastric curve 6 cm proximal to pylorus. Devascularization was done via either a harmonic scalpel or a ligasure device. Dissection was continued proximally till reaching the left diaphragmatic crus. Afterwards that the stomach was resected along the greater curvature via an endostapler over a 36-Fr bougie. After creating the sleeve, two meters of the small bowel were counted starting from the ligament of Treitz, and an antecolic isoperistaltic gastrojejunostomy (4-cm wide) was created with the antrum via linear stapler, and the anterior wall defect was closed by sutures.

single anastomosis sleeve jejunal bypass group

One anastomosis gastric bypass PROCEDURE

dissection started just distal to the crows' foot till reaching the lesser sac. A long narrow gastric pouch was created by the endostapler. After that, a longitudinal gastrojejunostomy (4-cm wide) was created at 200 cm distal to the Treitz ligament as the SASJ group.

one anastomosis gastric bypass

Eligibility Criteria

• Age: 16 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• body mass index of over 35 plus the comorbidity presence.
• body mass index of over 40 with/without comorbidity.
• patients' willingness to participate in the study.
• patients' cooperation in follow-up researches.
• lacking any psychiatric disease.

You may not qualify if:

• Patients negating to change their lifestyle.
• drug abuse and/or addiction.
• eating disorder background (e.g., bulimia nervosa).
• Patients with contraindications to laparoscopic surgery and (or) unfit for surgery.
• pregnant patients.
• previous upper abdominal procedures,
• reflux symptoms
• major unstable psychiatric illness.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University

Sohag, Egypt

Location

Study Officials

• sohag university hospital

  Sohag University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ashraf gamal

CONTACT

01019472023; ashraf_mohamed1@med.sohag.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant lecturer of general surgery at sohag university hospitals

Study Record Dates

• First Submitted: February 26, 2025
• First Posted: March 4, 2025
• Study Start: March 1, 2025
• Primary Completion: September 1, 2025
• Study Completion (Estimated): March 1, 2027
• Last Updated: March 11, 2025

Record last verified: 2025-03

Locations

EG (1)