Outcomes of Single Anastomosis Sleeve Jejunal Bypass (SAS-J) VS Sleeve Gastrectomy

NCT07413237 | Completed

• 1 other identifier: 13/8/2023.
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this work is to compare the outcomes of Single Anastomosis Sleeve Jejunal Bypass (SASJ) with sleeve gastrectomy as regards efficacy including sustained weight loss, metabolic syndrome, quality of life, complications and associated comorbidities in morbid obese.

Conditions

Single Anastomosis Sleeve Jejunal Bypass; Sleeve Gastrectomy

Outcome Measures

Primary Outcomes (1)

• Weight loss

  Weight loss was recorded.

  1 month after the procedure

Secondary Outcomes (3)

• Metabolic syndrome

  1 month after the procedure

• Assessment of quality of life

  1 month after the procedure

• Incidence of complications

  1 month after the procedure

Study Arms (2)

Group (A) (SASJ Group)

Patients underwent single anastomosis sleeve jejunal bypass as a metabolic and weight loss surgery.

Procedure: Single anastomosis sleeve jejunal bypass

Group (B) (Lap Gastric Sleeve Group)

Patients underwent laparoscopic sleeve gastrectomy(LGS) as a metabolic and weight loss surgery.

Procedure: Laparoscopic sleeve gastrectomy

Interventions

Single anastomosis sleeve jejunal bypass PROCEDURE

Patients underwent single anastomosis sleeve jejunal bypass as a metabolic and weight loss surgery.

Group (A) (SASJ Group)

Laparoscopic sleeve gastrectomy PROCEDURE

Patients underwent laparoscopic sleeve gastrectomy (LGS) as a metabolic and weight loss surgery.

Group (B) (Lap Gastric Sleeve Group)

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

This comparative prospective cohort study was conducted in General surgery department, Ain Shams University Hospitals.

You may qualify if:

• Patients age from 18 to 60 years old.
• Both sexes.
• Patients with body mass index (BMI) ≥ 40.
• Patients with BMI (35 - 40) with obesity related comorbidities. (e.g. type 2 diabetes mellitus, obstructive sleep apnea, hypertension, hyperlipidemia, obesity hypoventilation syndrome, non-alcoholic fatty liver disease, gastroesophageal reflux disease and severe arthritis).
• Able to be committed to follow-up.

You may not qualify if:

• Patients underwent previous Bariatric surgeries.
• Patients with severe systemic disease, such as congestive heart failure - unstable angina - recent stroke or myocardial infarction less than 3 months ago. Contraindications for insufflation as those with severe cardiovascular or severe restrictive respiratory diseases.
• Patients that refused to participate in the study.
• Patients with psychiatric illness.
• Preoperative upper GI endoscopy findings of GERD class C and Barrett's oesophagus
• Previous upper GIT surgery or liver cirrhosis.
• Patients on oral steroid therapy.
• Not fit for general anaesthesia (e.g. patients with severe heart disease or untreatable coagulopathies).
• Significant abdominal adhesions.
• Major psychiatric illness.
• Pregnant patients.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, 11591, Egypt

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Lecturer in General Surgery, Ain Shams University, Cairo, Egypt.

Study Record Dates

• First Submitted: February 10, 2026
• First Posted: February 17, 2026
• Study Start: August 15, 2023
• Primary Completion: August 1, 2025
• Study Completion: August 1, 2025
• Last Updated: February 17, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)