Pennington Generation Cohort

NCT06849206 | Recruiting

• 1 other identifier: 2024-036
• Study Type: observational
• Target: 3,000
• Locations: 1 country
• Sites: 1

Brief Summary

The Pennington Generation Cohort is an observational study comprised of Louisiana families. Families will be assessed at baseline for a variety of traits and behaviors, and then followed up over time to try to understand the role of lifestyle and the environment on the risk of developing obesity and other health outcomes.

Conditions

Obesity Prevention

Keywords

physical activity; obesity; diet; nutrition; families

Outcome Measures

Primary Outcomes (1)

• Obesity

  The development of obesity, defined using BMI z-scores during childhood, and BMI during adulthood.

  From enrollment up to 20 years of follow-up.

Secondary Outcomes (3)

• Weight change

  From enrollment up to 20 years of follow-up.

• Mortality

  From enrollment up to 20 years of follow-up..

• Cancer incidence

  From enrollment up to 20 years of follow-up..

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults of child-bearing age who are planning to become pregnant, expectant parents, as well as children, adolescents, and young adults and their nuclear family members will be recruited.

You may qualify if:

• Children, adolescents, and young adults (birth through age 24 years) and their nuclear family members\* and adults age 25+ who are expectant parents or are trying to conceive
• Self-reported resident of Louisiana
• Ability to understand instructions and complete all study procedures
• Able to provide informed consent (adults aged over 18 years)
• Able to provide assent (children 9 to 17 years)
• Able to communicate (oral and written) in English

You may not qualify if:

• Discretion of the Medical Monitor or Principal Investigator

Sponsors & Collaborators

• Pennington Biomedical Research Center: lead

Study Sites (1)

Pennington Biomedical Research Center

Baton Rouge, Louisiana, 70808, United States

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Saliva

MeSH Terms

Conditions

Motor Activity; Obesity

Condition Hierarchy (Ancestors)

Behavior; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Peter T Katzmarzyk, PhD

  Pennington Biomedical Research Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Peter T Katzmarzyk, PhD

CONTACT

225-763-2536; peter.katzmarzyk@pbrc.edu

Kara Denstel, PhD

CONTACT

763-2614; kara.denstel@pbrc.edu

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: February 19, 2025
• First Posted: February 27, 2025
• Study Start: February 24, 2025
• Primary Completion (Estimated): February 24, 2045
• Study Completion (Estimated): February 24, 2045
• Last Updated: March 17, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: Data will be made available 1 year after publication of the primary outcomes manuscript.
• Access Criteria: Upon reasonable request to the principal investigator and in alignment with the goals of the IRB-approved protocol.

Locations

US (1)