Soup Meal Satiety Study

NCT06771765 | Completed

• 1 other identifier: HS69 - Soup Meal Satiety Study
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

This study will investigate food ingredients that may provide fullness to healthy adults after a meal. The ingredients will be incorporated into a lunch meal, and measures of hunger and fullness will be evaluated for several hours after the meal. Study subjects must be able to travel to the USDA Nutrition Center in Beltsville Maryland at scheduled times during the study for meals and study measures.

Conditions

Obesity Prevention

Keywords

Satiety; Hunger; Fullness; Nutrition

Outcome Measures

Primary Outcomes (5)

• Feelings of Hunger

  Area Under the Curve for Visual Analogue Scale Assessment of Hunger versus Time

  0, 1, 2, 3, 4, 5, and 6 hours post treatment

• Feelings of Satisfaction

  Area Under the Curve for Visual Analogue Scale Assessment of Satisfaction versus Time

  0, 1, 2, 3, 4, 5, and 6 hours post treatment

• Feelings of Fullness

  Area Under the Curve for Visual Analogue Scale Assessment of Fullness versus Time

  0, 1, 2, 3, 4, 5, and 6 hours post treatment

• Desire to Eat

  Area Under the Curve for Visual Analogue Scale Assessment of Desire to Eat versus Time

  0, 1, 2, 3, 4, 5, and 6 hours post treatment

• Dinner Food Intake

  Weight of food eaten at dinner

  5 hours post intervention

Study Arms (3)

Control Lunch Meal

PLACEBO COMPARATOR

A lunch meal will be provided that is comprised of soup, bread, and a cookie. These items will be made from standard recipes. This arm will be a placebo comparator to meals made with chia seeds or hemp seeds, which may provide extra satiety.

Other: Control (placebo) group

Chia Enriched Lunch Meal

EXPERIMENTAL

A lunch meal will be provided that is comprised of soup, bread, and a cookie. These items will be made from standard recipes that have been enhanced with chia seeds, which may provide extra satiety compared to the standard recipes in the placebo arm.

Other: Chia Seeds

Hemp Enriched Lunch Meal

EXPERIMENTAL

A lunch meal will be provided that is comprised of soup, bread, and a cookie. These items will be made from standard recipes that have been enhanced with hemp seeds, which may provide extra satiety compared to the standard recipes in the placebo arm.

Other: Hemp Seeds

Interventions

Chia Seeds OTHER

Chia seeds will be added to soup, bread, and a cookie, and these food items will be served as a lunch meal.

Chia Enriched Lunch Meal

Hemp Seeds OTHER

Hemp seeds will be added to soup, bread, and a cookie, and these food items will be served as a lunch meal.

Hemp Enriched Lunch Meal

Control (placebo) group OTHER

This intervention is a lunch meal made from standard recipes. This intervention is the placebo control intervention.

Control Lunch Meal

Eligibility Criteria

• Age: 25 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may not qualify if:

• Younger than 25 years
• Known (self-reported) allergy or adverse reaction to study foods
• Women who have given birth during the previous 12 months or who are pregnant/lactating or who plan to become pregnant over the upcoming 6 months (thus during the study period)
• Presence of diabetes, diverticulitis, colitis, celiac disease, Crohn's disease, irritable bowel syndrome, gastrointestinal disease, pancreatic disease
• History of bariatric surgery or other weight control surgery
• Removal of a portion of the stomach or gastrointestinal tract
• Actively trying to gain or lose weight at the time of the study recruitment or planning to gain or lose weight during the study periods
• Diminished sense of taste and/or smell
• Anorexia Nervosa and/or Bulimia
• Smoking, vaping, or use of tobacco products in the past 3 months
• Suspected or known physiological/mechanical GI obstruction
• Use of certain medications or supplements (prescription or over-the-counter) that may interfere with the study objectives
• Unable or unwilling to give informed consent or communicate with study staff
• Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol

Sponsors & Collaborators

• USDA Beltsville Human Nutrition Research Center: lead

Study Sites (1)

U.S. Department of Agriculture, Beltsville Human Nutrition Research Center

Beltsville, Maryland, 20705, United States

Location

MeSH Terms

Interventions

Population Groups

Intervention Hierarchy (Ancestors)

Demography; Population Characteristics

Study Officials

• Janet Novotny, PhD

  United States Department of Agriculture (USDA)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: FED
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Physiologist

Study Record Dates

• First Submitted: January 7, 2025
• First Posted: January 13, 2025
• Study Start: February 18, 2025
• Primary Completion: May 2, 2025
• Study Completion: May 2, 2025
• Last Updated: August 22, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)