Uric Acid and Surgical Prognosis

NCT06837545 | Completed

• 1 other identifier: AMC (2024-1090)
• Study Type: observational
• Target: 309,353
• Locations: 1 country
• Sites: 1

Brief Summary

Preoperative serum uric acid significantly impacted mortality and morbidity in non-cardiac surgery.

Conditions

Uric Acid

Keywords

Uric Acid; Mortality; Surgical Prognosis; Acute Kidney Injury

Outcome Measures

Primary Outcomes (1)

• 30-day postoperative mortality

  The primary outcome measure is the incidence of 30-day postoperative mortality in patients undergoing non-cardiac surgeries. Mortality is defined as death occurring within 30 days following the surgery.

  30 days post-surgery

Interventions

No Intervention (Observational Study) OTHER

This study is an observational analysis of preoperative serum uric acid levels and their association with postoperative outcomes. No intervention was administered."

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population includes adult patients aged 18 years or older who underwent non-cardiac surgeries at a tertiary hospital. Patients with emergency surgeries, pregnancy, cadavers, and incomplete data with missing preoperative uric acid levels, or missing follow-up information were excluded from the analysis. The study focuses on evaluating the impact of preoperative uric acid on postoperative outcomes, including mortality and morbidities.

You may qualify if:

• Patients aged 18 years or older
• Patients who underwent non-cardiac surgery

You may not qualify if:

• Emergency surgery
• Pregnancy
• Cadavers
• Patients with missing preoperative SUA values or no follow-up after surgery

Sponsors & Collaborators

• Asan Medical Center: lead

Study Sites (1)

Asan Medical Center

Seoul, Songpa, 05505, South Korea

Location

MeSH Terms

Conditions

Acute Kidney Injury

Interventions

Observation

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Intervention Hierarchy (Ancestors)

Methods; Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: February 15, 2025
• First Posted: February 20, 2025
• Study Start: July 30, 2024
• Primary Completion: December 20, 2024
• Study Completion: January 2, 2025
• Last Updated: February 20, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)