NCT06836375

Brief Summary

The objective of this study is to detect the acoustic signals generated by the respiratory system on asthma patients using an acoustic sensor and retrospectively use these signals to identify the characteristics that differentiate patients with asthma and healthy subjects.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
10mo left

Started Sep 2025

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress43%
Sep 2025Feb 2027

First Submitted

Initial submission to the registry

February 13, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 20, 2025

Completed
7 months until next milestone

Study Start

First participant enrolled

September 27, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 27, 2026

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

February 27, 2027

Expected
Last Updated

August 19, 2025

Status Verified

February 1, 2025

Enrollment Period

5 months

First QC Date

February 13, 2025

Last Update Submit

August 14, 2025

Conditions

Keywords

Asthma

Outcome Measures

Primary Outcomes (1)

  • Acoustic respiratory signals

    Acoustic signals during the tests performed for asthma diagnosis and while the subjects sleep for at least two weeks.

    During the diagnostic tests performed and during the night studies performed by the participant for at least two weeks

Study Arms (2)

Patients with Bronchial asthma

Patients with a diagnosis of bronchial asthma, under follow-up by the Asthma Unit.

Diagnostic Test: Spirometry test with bronchodilationDiagnostic Test: Methacholine challengeDiagnostic Test: impulse oscillometryOther: Measurement of the exhaled FeNO fraction

Patients referred for consultation

Patients referred for consultation due to clinical suspicion of bronchial asthma.

Diagnostic Test: Spirometry test with bronchodilationDiagnostic Test: Methacholine challengeDiagnostic Test: impulse oscillometryOther: Measurement of the exhaled FeNO fraction

Interventions

this test measures how much air you can breathe in and out of your lungs, as well as how easily and fast you can then blow the air out of your lungs

Patients referred for consultationPatients with Bronchial asthma
Methacholine challengeDIAGNOSTIC_TEST

test used to diagnose asthma where the patient breaths in methacholine

Patients referred for consultationPatients with Bronchial asthma
impulse oscillometryDIAGNOSTIC_TEST

test that uses sound waves to measure how much resistance there is to the normal movement of air in and out of your lungs when you are breathing at rest

Patients referred for consultationPatients with Bronchial asthma

Measure the level of nitric oxide in parts per billion (PPB) in the air the patient slowly exhales

Patients referred for consultationPatients with Bronchial asthma

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients from or referred to the asthma unit in the hospital Virgen del Rocio in Seville, Spain

You may qualify if:

  • Male or female, aged \>= 18 and \< 65.
  • Ability to access applications on mobile device, technical understanding and minimal technological skills
  • Subject has provided informed consent and is willing to comply with the study procedures.

You may not qualify if:

  • Subject does not consent to the study
  • Subject has a known allergy to medical adhesives

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Virgen del Rocio

Seville, Spain

Location

MeSH Terms

Conditions

Asthma

Interventions

Spirometry

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

Respiratory Function TestsDiagnostic Techniques, Respiratory SystemDiagnostic Techniques and ProceduresDiagnosis

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 13, 2025

First Posted

February 20, 2025

Study Start

September 27, 2025

Primary Completion

February 27, 2026

Study Completion (Estimated)

February 27, 2027

Last Updated

August 19, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations