NCT06824727

Brief Summary

The purpose of the research project is to collect one blood sample from participants who are affected by very low platelets as a result of their condition or their treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 6, 2025

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 12, 2025

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 13, 2025

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 21, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 21, 2025

Completed
Last Updated

September 5, 2025

Status Verified

September 1, 2025

Enrollment Period

8 months

First QC Date

February 12, 2025

Last Update Submit

September 4, 2025

Conditions

Thrombocytopenia

Keywords

Stem Cell Transplant

Outcome Measures

Primary Outcomes (1)

  • Sample collection of peripheral blood from patients experiencing thrombocytopenia

    Baseline

Study Arms (1)

Sample Collection

Other: Baseline cell blood counts

Interventions

Baseline cell blood countsOTHER

Obtain one peripheral blood sample from participants who have severe thrombocytopenia defined as 30,000 platelets/mcl or less

Sample Collection

Eligibility Criteria

Age18 Years - 88 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Samples will be collected from participants from the bone marrow transplant inpatient service and outpatient clinics.

You may qualify if:

  • Adults 18 years or older
  • Platelet counts of 30,000/mcl or less

You may not qualify if:

  • Chemotherapy within the last 24 hours from the planned blood sample draw for research purposes.
  • Use of anticoagulant agents in the last 48 hours.
  • Active infection (i.e. one that has received less than 48 hours of active treatment).
  • Adults 89 years or older

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute

Cleveland, Ohio, 44195, United States

Location

MeSH Terms

Conditions

Thrombocytopenia

Condition Hierarchy (Ancestors)

Blood Platelet DisordersHematologic DiseasesHemic and Lymphatic DiseasesCytopenia

Study Officials

  • Paolo Caimi, MD

    Case Comprehensive Cancer Center, Cleveland Clinic Taussig Cancer Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 12, 2025

First Posted

February 13, 2025

Study Start

January 6, 2025

Primary Completion

August 21, 2025

Study Completion

August 21, 2025

Last Updated

September 5, 2025

Record last verified: 2025-09

Locations

US(1)