NCT06822595

Brief Summary

This study investigates the effects of high-load BFR training on anaerobic performance and fatigue resistance in distance runners. To determine whether adding BFR to isokinetic resistance training improves anaerobic performance and 5-10 km running times in runners. Forty-two runners were randomized into BFR (n=21) and control (n=21) groups. Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure. Anaerobic performance was assessed via the Wingate test, and 5 km and 10 km running times were recorded before and after the intervention. Statistical analyses compared pre- and post-training performance within and between groups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2022

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 15, 2022

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 15, 2023

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 15, 2024

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

February 2, 2025

Completed
10 days until next milestone

First Posted

Study publicly available on registry

February 12, 2025

Completed
Last Updated

February 12, 2025

Status Verified

February 1, 2025

Enrollment Period

10 months

First QC Date

February 2, 2025

Last Update Submit

February 6, 2025

Conditions

Anaerobic Performance

Keywords

AthletemuscularKAATSUsports medicineperformance

Outcome Measures

Primary Outcomes (1)

  • The effects of an isokinetic training program combined with blood flow restriction (BFR) on anaerobic performance and fatigue resistance in long-distance runners were investigated.

    Lower extremity Wingate Test (WanT) was used to evaluate the anaerobic capacities of long-distance runners. In calculating the fatigue index; (peak power - minimum power/peak power) x 100 (% fatigue index) formula was used.

    baseline and week 8

Study Arms (2)

Blood flow restriction (BFR) Group

EXPERIMENTAL

BFR group followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure.

Device: Blood flow restriction (BFR) trainingDevice: Isokinetic training

Control Group

ACTIVE COMPARATOR

Control group followed an identical 8-week isokinetic training protocol twice weekly.

Device: Isokinetic training

Interventions

Blood flow restriction (BFR) trainingDEVICE

Both groups followed an identical 8-week isokinetic training protocol twice weekly. The BFR group performed exercises with arterial occlusion pressure set to 80% of the measured occlusion pressure.

Also known as: Isokinetic training
Blood flow restriction (BFR) Group
Isokinetic trainingDEVICE

Both groups followed an identical 8-week isokinetic training protocol twice weekly.

Blood flow restriction (BFR) GroupControl Group

Eligibility Criteria

Age22 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • The absence of cardiovascular or musculoskeletal conditions,
  • No recent resistance training,
  • Running more than 20 kilometers per week.

You may not qualify if:

  • Having a cardiovascular or musculoskeletal condition,
  • Having done recent resistance training,
  • Running less than 20 kilometers per week.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Hüseyin Günaydın

Ankara, 06018, Turkey (Türkiye)

Location

University of Health Sciences, Gulhane Faculty of Medicine

Ankara, 06018, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Blood Flow Restriction Therapy

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy Modalities

Study Officials

  • Hüseyin Günaydın

    University of Health Sciences, Gulhane Faculty of Medicine, Ankara/Türkiye

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
associate professor

Study Record Dates

First Submitted

February 2, 2025

First Posted

February 12, 2025

Study Start

July 15, 2022

Primary Completion

May 15, 2023

Study Completion

July 15, 2024

Last Updated

February 12, 2025

Record last verified: 2025-02

Locations

TU(2)