NCT01770288

Brief Summary

During anaerobic exercise, the metabolic pathway of glycolysis is used in order to produces high-energy compounds adenosine triphosphate (ATP).The level of lactic acid in the blood is a marker to the increased protons concentration and acidosis.nevertheless, the increased level of protons in addition to the release of bradykinin causes pain during the exercise that limited the subject's performance. Therefore, it is assumed that the individual pain sensitivity might determine the subject's performance. Aims: To investigate the role of the DNIC efficiency in prediction of anaerobic performance in humans (2) to study the role of peripheral pro-nociceptive processing in mediating pain during anaerobic exercise and its contribution to the subjects' performance (3) to assess the function of pain-related psychological factors in anaerobic performance.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2013

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 6, 2013

Completed
11 days until next milestone

First Posted

Study publicly available on registry

January 17, 2013

Completed
15 days until next milestone

Study Start

First participant enrolled

February 1, 2013

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2013

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2013

Completed
Last Updated

January 17, 2013

Status Verified

January 1, 2013

Enrollment Period

Same day

First QC Date

January 6, 2013

Last Update Submit

January 15, 2013

Conditions

Keywords

Anerobic exercisePainAnalgesiaDiffuse Noxious Inhibitory Control (DNIC)psychological stress

Outcome Measures

Primary Outcomes (1)

  • Pain psychophysics tests

    DNIC will be tested using a paradigm of two remote noxious stimuli with one, the 'conditioning stimulus' (immersing the hand in tub containing 8°c water), inhibiting the other, the 'test pain' (pressure pain threshold) in order to assess the EA efficiency (2) heat and pressure pain thresholds, and (3) temporal summation of painful heat and mechanical stimuli that reflect the neuroplasticity of the central nervous system following peripheral noxious stimulation.

    1 year

Secondary Outcomes (2)

  • Lactate concentration

    1 year

  • The anaerobic performance

    1 year

Study Arms (1)

Anaerobic Performance

EXPERIMENTAL
Other: Anaerobic wingate test

Interventions

Anaerobic Performance

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy Volunteers

You may not qualify if:

  • pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zinman College for Physical Education and Sport Sciences at the Wingate Institute

Netanya, 42902, Israel

Location

MeSH Terms

Conditions

PainAgnosiaStress, Psychological

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsPerceptual DisordersNeurobehavioral ManifestationsNervous System DiseasesBehavioral SymptomsBehavior

Study Officials

  • Einat Kodesh, PhD

    University of Haifa

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Einat Kodesh, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 6, 2013

First Posted

January 17, 2013

Study Start

February 1, 2013

Primary Completion

February 1, 2013

Study Completion

April 1, 2013

Last Updated

January 17, 2013

Record last verified: 2013-01

Locations