NCT06822101

Brief Summary

The purpose of this study is to investigate how our performance changes after our perceptual system is trained in a certain way ("perceptual learning"). In addition, we are interested in identifying and characterizing relationships between such changes and neuroimaging signals recorded from the human brain.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable

Timeline
25mo left

Started Feb 2025

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress37%
Feb 2025May 2028

First Submitted

Initial submission to the registry

February 3, 2025

Completed
8 days until next milestone

Study Start

First participant enrolled

February 11, 2025

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 12, 2025

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2028

Last Updated

May 2, 2025

Status Verified

April 1, 2025

Enrollment Period

3.3 years

First QC Date

February 3, 2025

Last Update Submit

April 29, 2025

Conditions

Keywords

Behavioral

Outcome Measures

Primary Outcomes (1)

  • Behavioral measure

    Changes in rates of correct detection or discrimination in behavioral visual tasks after training are measured.

    From enrollment to the end of treatment at 2 weeks.

Interventions

Visual TrainingBEHAVIORAL

Participants are asked to detect or discriminate visual stimuli.

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Ages 18 - 60,
  • Normal or corrected-to-normal vision

You may not qualify if:

  • Eye disorders (cataracts, age related macular degeneration, diabetic retinopathy, glaucoma)
  • Drug use (psychoactive drugs, neuroleptic medications, prescription medications that might affect cognitive and motor performance)
  • Sleep disorders (sleep apnea, insomnia)
  • Magnetically or mechanically activated implants (such as cardiac pacemakers)
  • clips on blood vessels in the brain
  • intrauterine devices
  • dentures
  • pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Brown University

Providence, Rhode Island, 02912, United States

Location

Related Publications (3)

  • Seitz AR, Kim D, Watanabe T. Rewards evoke learning of unconsciously processed visual stimuli in adult humans. Neuron. 2009 Mar 12;61(5):700-7. doi: 10.1016/j.neuron.2009.01.016.

    PMID: 19285467BACKGROUND
  • Sasaki Y, Nanez JE, Watanabe T. Advances in visual perceptual learning and plasticity. Nat Rev Neurosci. 2010 Jan;11(1):53-60. doi: 10.1038/nrn2737. Epub 2009 Dec 2.

    PMID: 19953104BACKGROUND
  • Watanabe T, Sasaki Y. Perceptual learning: toward a comprehensive theory. Annu Rev Psychol. 2015 Jan 3;66:197-221. doi: 10.1146/annurev-psych-010814-015214. Epub 2014 Sep 10.

    PMID: 25251494BACKGROUND

MeSH Terms

Conditions

Behavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Fred M. Seed Professor

Study Record Dates

First Submitted

February 3, 2025

First Posted

February 12, 2025

Study Start

February 11, 2025

Primary Completion (Estimated)

May 31, 2028

Study Completion (Estimated)

May 31, 2028

Last Updated

May 2, 2025

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will share

The types of data to be produced in the current project will be behavioral data and participants' demographic information will also be collected. All data will be de-identified before receipt by the repository. Programs for visual stimuli and data analyses will be produced in the project.

Shared Documents
ANALYTIC CODE

Locations