Duration of Postop Analgesia After Inguinal Hernia Surgery Treated with TAP Block Vs II/IH Nerve Block

NCT06812741 | Completed Phase 3

• 1 other identifier: 530/ 2024
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Comparing Postop Analgesia after Inguinal Hernia Surgery treated with TAP Block Vs Ilioinguinal/ Iliohypogastric Nerve Block

Conditions

Postoperative Analgesia

Keywords

postop analgesia; postoperative analgesia; TAP block; transversus abdominis plane block; ilioinguinal/ iliohypogastric nerve block; ilioinguinal/iliohypogastric nerve block; inguinal hernia surgery; abdominal nerve block; nerve block; nerve blocks; bupivacaine; ultrasound guided nerve block; ultrasound guided nerve blocks; 0.25% bupivacaine; 0.25 percent bupivacaine; hernioplasty; internal oblique; transversus abdominis; IIN; IHN; IIN/ IHN; II/ IH nerve block; transversus abdominis muscle; ilioinguinal muscle; iliohypogastric muscle

Outcome Measures

Primary Outcomes (1)

• Mean duration of Postoperative Analgesia

  The study was conducted to compare the mean duration of postoperative analgesia in patients undergoing inguinal hernia repair surgery treated with transversus abdominis plane block versus the mean duration of postoperative analgesia in patients undergoing inguinal hernia repair surgery treated with ilioinguinal and iliohypogastric nerve block.

  6 months

Study Arms (2)

Inguinal Hernia Surgery (Group T)

EXPERIMENTAL

Half of the study participants named Group T were administered Ultrasound Guided Transversus Abdominis Plane Nerve Block and the other half named Group I were administered Ilioinguinal \& Iliohypogastric Nerve Block before the Inguinal Hernia Surgery.

Drug: Transversus abdominis plane (TAP) block with 0.25 % bupivacaine

Inguinal Hernia Surgery (Group I)

EXPERIMENTAL

Half of the study participants named Group T were administered Ultrasound Guided Transversus Abdominis Plane Nerve Block and the other half named Group I were administered Ilioinguinal \& Iliohypogastric Nerve Block before the Inguinal Hernia Surgery.

Drug: Ilioinguinal/iliohypogastric Nerve Block with 0.25 % bupivacaine

Interventions

Transversus abdominis plane (TAP) block with 0.25 % bupivacaine DRUG

The probe was placed in a plane transverse to the lateral abdominal wall in the mid-axillary line immediately cephalad to the iliac crest. The needle was advanced immediately anterior to the probe using the in-plane needle-probe orientation and advanced posteriorly until the needle was observed to penetrate the interface between the internal oblique and transversus abdominis muscles. Thereafter, a local anesthetic (0.2 mL/kg of 0.25 % bupivacaine) was injected incrementally, and the spread was observed within the plane.

Inguinal Hernia Surgery (Group T)

Ilioinguinal/iliohypogastric Nerve Block with 0.25 % bupivacaine DRUG

The ultrasound probe was placed immediately medial and slightly cephalad to the upper aspect of the anterior superior iliac spine to obtain a short-axis view of the nerves situated between the two abdominal muscles (internal oblique and transversus abdominis), A 22 G needle tip \~1 cm caudal to the probe surface was introduced and was advanced until a characteristic 'tenting' of the interface between the two muscles was seen and was then further advanced deep to this interface until a pop was felt and then the injectate (0.2 mL/kg of 0.25 % bupivacaine) was observed spreading between these two layers.

Inguinal Hernia Surgery (Group I)

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients giving written informed consent
• Patients undergoing Inguinal Hernia surgery
• patients with ages 18-60 years
• ASA 1 and 2 patients

You may not qualify if:

• INR \> 1.0 (patients with bleeding tendency)
• EF \< 45 % (patients with cardiac dysfunction)
• FEV1 \< 80 % of normal (patients with pulmonary dysfunction)
• patients with renal disease

Sponsors & Collaborators

• Pakistan Navy Station Shifa Hospital: lead

Study Sites (1)

Combined Military Hospital Lahore

Lahore, Punjab Province, Pakistan

Location

MeSH Terms

Interventions

Dental Occlusion; Bupivacaine

Intervention Hierarchy (Ancestors)

Dentistry; Dental Physiological Phenomena; Digestive System and Oral Physiological Phenomena; Anilides; Amides; Organic Chemicals; Aniline Compounds; Amines

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: FCPS Registrar in Anaesthesia

Study Record Dates

• First Submitted: February 2, 2025
• First Posted: February 6, 2025
• Study Start: February 9, 2024
• Primary Completion: July 28, 2024
• Study Completion: July 28, 2024
• Last Updated: February 28, 2025

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)