Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries

NCT06809842 | Recruiting

• 1 other identifier: MKSU 50-1-4
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare the analgesic efficacy and functional outcomes of blocking the nerve to the vastus lateralis (NVL) muscle versus the lateral femoral cutaneous nerve (LFCN).

Conditions

Analgesia; Vastus Lateralis Nerve Block; Lateral Femoral Cutaneous Nerve Block; Knee Surgeries

Outcome Measures

Primary Outcomes (1)

• Degree of pain

  Each patient will be instructed about postoperative pain assessment using the numeric rating scale (NRS) score (0 represents "no pain" while 10 represents "the worst pain imaginable"). NRS assessments will be conducted at the post-anesthesia care unit (PACU) and at 2, 4, 6, 12, 18, and 24 hours postoperatively.

  24 hours postoperatively

Secondary Outcomes (6)

• Time to first request for analgesia

  24 hours postoperatively

• Total morphine consumption

  24 hours postoperatively

• Block performance time

  Intraoperatively

• Degree of patient satisfaction

  24 hours postoperatively

• Length of hospital stay

  Till the discharge from hospital (Up to one week).

Study Arms (2)

Vastus lateralis nerve block group

EXPERIMENTAL

Patients will receive vastus lateralis nerve block.

Drug: Vastus lateralis nerve block

Lateral femoral cutaneous nerve block group

EXPERIMENTAL

Patients will receive lateral femoral cutaneous nerve.

Drug: Lateral femoral cutaneous nerve block

Interventions

Vastus lateralis nerve block DRUG

Patients received vastus lateralis nerve block with 5 ml of bupivacaine 0.5%.

Also known as: Bupivacaine 0.5%

Vastus lateralis nerve block group

Lateral femoral cutaneous nerve block DRUG

Patients received lateral femoral cutaneous nerve block with 5 ml of bupivacaine 0.5%.

Also known as: Bupivacaine 0.5%

Lateral femoral cutaneous nerve block group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥ 18 years.
• Both sexes.
• American Society of Anesthesiologists (ASA) physical status from I to III.
• Underwent knee surgeries under spinal anesthesia.

You may not qualify if:

• Pregnancy.
• Coagulopathy.
• Neuromuscular disorders.
• Hematological disorders.
• Mental disorders.
• History of multiple traumas or anesthesia drug allergies.
• Local skin infection at the block site.
• Body mass index (BMI) greater than 40.
• Opioid analgesics or abusing opioids.

Sponsors & Collaborators

• Kafrelsheikh University: lead

Study Sites (1)

Kafrelsheikh University

Kafr ash Shaykh, Kafrelsheikh, 33516, Egypt

RECRUITING

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Sherif K Arafa, MD

CONTACT

00201005714014; Sherifhafez1980@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor of Anesthesiology, Surgical Intensive Care and Pain Management Department, Faculty of Medicine, KafrElsheikh University, KafrElsheikh, Egypt.

Study Record Dates

• First Submitted: January 30, 2025
• First Posted: February 5, 2025
• Study Start: February 5, 2025
• Primary Completion: July 30, 2025
• Study Completion: July 30, 2025
• Last Updated: February 6, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)